1 / 8

Petr Widimský, Zuzana Moťovská

PRAGUE-14 Perioperative cardiovascular complications versus perioperative bleeding in patients with cardiovascular disease undergoing non- cardiac surgery . Petr Widimský, Zuzana Moťovská

salene
Download Presentation

Petr Widimský, Zuzana Moťovská

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PRAGUE-14Perioperativecardiovascularcomplications versus perioperativebleedingin patientswithcardiovasculardiseaseundergoing non-cardiacsurgery. Petr Widimský, Zuzana Moťovská Lukáš Havlůj, Martina Ondráková, Radek Bartoška, Lukáš Bittner, *Ladislav Dušek, Valér Džupa, Jiří Knot, Martin Krbec, Libor Mencl, Jan Pachl, Robert Grill, Pavel Haninec, Petr Waldauf, Robert Gürlich University Hospital Kralovske Vinohrady Prague, CZ

  2. Patients, type ofsurgery Enrollingsurgicaldepartments: Generalsurgery (43,3% pts) Trauma / orthopedicsurgery (39,9%) Urology (10,5%) Neurosurgery (5,5%) Anesthesiology (0,8%) Study design, coordination, data analysis:Cardiology N = 1211 (allpts. with CV diseaseundergoing major non-cardiacsurgeryduringthe study period 2011–13 (6,3% of 18 951 surgicalpts) Generalanesthesiain 64,4%

  3. In-hospital mortality of patientswith a cardiovasculardisease (n=1200) vs. thosewithout CVD (n=17740)

  4. Duration of ASA interruptionin subgroups per complication type p<0.001 p=0.027 n.s.

  5. ASA interruption[days] vs. complication risk [%]

  6. Risk factorsforcomplications (multivariantanalysis) Cardiovascularcomplications Bleedingcomplications

  7. How to interpret data on ASA interruption ? • Patientswithno (oronlyshort) ASA interruptionbeforesurgery had more bleedingcomplications as well as more cardiovascularcomplicationsthenthose in whom ASA wasstoppedatleastoneweekbeforesurgery. • However, multivariatestatisticalanalysisdidnotfoundthis to bean INDEPENDENT factor. • Most likelythisisrelated to thefact, thatshort ASA interruptionwasmostlyamongpatientsundergoingacutesurgery (withinherenthigher risk) • A more detailedanalysisfocused on a subgroupofelectivesurgicalpatientsisplanned

  8. Conclusion • Perioperativecardiovascularcomplications in non-selectedptswithcardiovasculardiseaseswhoundergo non-cardiacsurgery are rare. • Antithrombotictherapyinterruptionshortlybeforesurgerywas not associatedwithlower risk of perioperativecardiovascularcomplications in theoverallpopulation • Amongelectivesurgicalpatientstherewas a trend towardsincreased risk ofcomplicationswhen ASA wasstopped 4-8 days prior to surgery.

More Related