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Clinical research career development Ian Hall Chair, MRC Clinical Training Fellowship Panel

Clinical research career development Ian Hall Chair, MRC Clinical Training Fellowship Panel. Three MRC Fellowship groups Non Clinical , Clinical and some of Strategic Skill fellowships. Senior Non-Clinical. Career Development Award. Yrs Post PhD. CRTF. Clinical Lectureship.

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Clinical research career development Ian Hall Chair, MRC Clinical Training Fellowship Panel

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  1. Clinical research career development Ian Hall Chair, MRC Clinical Training Fellowship Panel

  2. Three MRC Fellowship groups Non Clinical, Clinical and some of Strategic Skillfellowships Senior Non-Clinical Career Development Award Yrs Post PhD CRTF ClinicalLectureship Clinician Scientist Senior ClinicalLectureship Senior Clinical Population Health Science Biomed informatics, Biostats, Economics of Health Methodology Development

  3. MRC has a leading role and complementary partnerships in clinical research training

  4. “My fellowship led directly to more opportunities and collaborations…” MRC Clinician Scientist Fellow Resources Protected time Connections, networks Potential to establish competitive position Route to independence Recognition Influence Fellowships: More than just a grant! Great opportunities Outstanding researchers

  5. Example of partnership with the Academy of Medical Sciences 3 month Policy Internships £30k CL Starter Grants

  6. Clinical Fellowships Clinical Scientist fellowship Aim to develop outstanding clinically qualified professionals who have gained a PhD/DPhil to establish themselves as independent researchers.  Up to 4 years' support (or 5 years if 40% clinical work involved) Support: fellow’s salary + research expenses (including research support staff) + travel Average cost per award = approximately £1m. www.mrc.ac.uk

  7. Clinical Fellowships Senior Clinical fellowship Aimed at clinical researchers who are independent researchers Must have a PhD/MD + at least 3 years post-doctoral research experience, and they must not hold a tenured academic position. 5 years support…. Around £1.5-2.0m.

  8. Fellowships The person The project The ‘place’ Grants The project / programme The people The ‘place (s)’ “The thing I enjoy so much is that my work has direct application to people…” MRC/Academy of Medical Sciences Clinician Scientist Great opportunities MRC Research Fellows Outstanding researchers

  9. Advancing shared interests Exchange of knowledge Access to technologies Access to quality-assured libraries, banks Route to translation Understanding of commercial needs & decision-making Working with industry: Potential benefits Great opportunities “Ultimately, if you want to have a positive impact on patients, then you need industry’s support.” MRC Senior Non-Clinical Fellow

  10. Great outcomes for MRC clinician PhDs (CRTFs) training in 1991 57% FMedSci 8 FMedSci

  11. Great outcomes for clinician PhDs: Sample of 1993-2003 Clinical Research Training Fellows 88% of ex-fellows in academic posts are clinically active 65% spend >25% of time on clinical activities Most direct or lead research • 27% now hold a senior clinical position • 65% now hold a senior academic position • ~80% of ex-fellows in fully clinical posts are research active • Most spend <25% of time on research • Most contribute to research led by others

  12. Early career researchers are not just ‘pairs of hands’ Choose inspirational supervisors / leaders Take responsibility for your project Don’t go any old ‘Bad Project…!’ http://www.youtube.com/watch?v=Fl4L4M8m4d0 In developing your career, choosecarefully

  13. Understand how peer review works • National Institutes of Health (NIH) • http://www.youtube.com/watch?v=fBDxI6l4dOA External referees 3 per 3-yr Proposal Reports & scores Shortlisting By Committee subgroup Committee scores & ranks Committee feedback Learn from your mentors, peers & funders how peer review works March 2012 13

  14. Writing fellowship & grant proposals • Don’t be boring (“So what?”) • Be ambitious, original and credible • Structure a clear, logical plan to achieve challenging objectives • Explain pilot data & others’ inputs • Risks are inevitable: Have a Plan B • Write clearly, for experts & non-experts in your field. Make your proposal easy to read! • Invite tough criticism from peers, mentors & friends before you submit Excite & don’t annoy your reviewers

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