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R 2 =0.98

A. E13.5. R 2 =0.98. 1.0. Control. R 2 =0.99. 0.8. Ts=5. 2 hr Tc=11. 0 hr. 0.6. Labeling Index (LI). PS cDKO. 0.4. Ts=5. 3 hr Tc=10. 5 hr. 0.2. 0. 1. 2. 3. 4. 5. 6. 7. 8. Length of BrdU pulse (hr). B. GF. Labeling Index (LI). slope =GF/Tc. Tc-Ts. GFx(Ts/Tc).

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R 2 =0.98

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  1. A E13.5 R2=0.98 1.0 Control R2=0.99 0.8 Ts=5.2 hr Tc=11.0 hr 0.6 Labeling Index (LI) PS cDKO 0.4 Ts=5.3 hr Tc=10.5 hr 0.2 0 1 2 3 4 5 6 7 8 Length of BrdU pulse (hr) B GF Labeling Index (LI) slope=GF/Tc Tc-Ts GFx(Ts/Tc) Length of BrdU pulse (hr)

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