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Standardization of methods

Standardization of methods . Sample standards Synthetic standard SOP’s Instrument standardisation Normalisation (intra- and interbatch ) Pre-processing of data. Sample standards . NIST + local pool sample (plasma) Calibrate the local pool to the NIST

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Standardization of methods

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  1. Standardization of methods • Sample standards • Synthetic standard • SOP’s • Instrument standardisation • Normalisation (intra- and interbatch) • Pre-processing of data

  2. Sample standards • NIST + local pool sample (plasma) • Calibrate the local pool to the NIST • Local pool production SOP (method dev. /QC/etc) • Jean-Charles Martin, Richard Beger, Anne-Marie Bayle, Ronald Aardema • Urine • Anybody making a representative sample? Lars • Tissue • White adipose tissue (human), Muscle & Liver (animal/cow/pig) • Anybody hospital contacts? • Faecal samples?

  3. Synthetic standard • Feedback required A.S.A.P. • Performance indicators • Coverage, Improve quantitation?, System performance indicator, use as intra/inter-batch corrector? • Send SOP out to volunteers/new version will be uploaded soon • Send a mail to ThaerBarri

  4. SOP’s • Version control • Blog, automatic mail/reminders (new version/alert for update • Sample shipment SOP • Thaer, Ivana Bobeldijk, John Newman(?), Rob Vreeken • Batch build-up • Ronald, Daniela

  5. Instrument Standardisation • Best practices/routines/SST(synthetic standard) • Jean-Charles Martin, Rob, Thaer, John Newman(?)

  6. Pre-processing of data • Inventory of used strategies • Jildau • Collection of R-procedures to go into Excel • John Newman, Bruce Kristal, Manfred, Adrie Dane

  7. Working committee • Rob Vreeken • Lars OveDragsted • Jildau Bauman • Jean Charles Martin • Ronald Aardema • Richard Beger • Estelle Pujos • Mark Philo • Sonja Peters • Maria Vinaixa • MetteSkouHedermann • Marie-Laure Bayle • Thaer Bari • Miguel Rodriguez • John Newman • Ivana Bobeldijk-Pastorova

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