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Multifunctional PDMS tips fabricated by polymer casting of KOH etched pyramidal p its. First Presentation; Project Defence. Kees Schilder. Introduction. Polymer tip array Increase of throughput Challenge is inclination of tip array Advantage of PDMS Compliance Stiffness. Applications.
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Multifunctional PDMS tips fabricated by polymer casting of KOH etched pyramidal pits First Presentation; Project Defence Kees Schilder
Introduction • Polymer tip array • Increase of throughput • Challenge is inclination of tip array • Advantage of PDMS • Compliance • Stiffness
Applications • Proteome analysis • Cleaning • Direct write lithography C. Wingrenet al., Progress in miniaturization of protein arrays – a step closer to high-density nanoarrays, Drug Discovery Today (2007) F. Huoet al., Polymer Pen Lithography, Science (2008)
Fabrication Process - Pits & Holes – 1.1 Fabrication Process - Pits & Holes – 1.2
Fabrication Process - Pits & Holes – 2.1 Fabrication Process - Pits & Holes – 2.2 Fabrication Process - Pits & Holes – 2.3
Mask Design • Simple design • Various configurations
Timeline - Milestones What has to be done What has been done
Expected Challenges • Producing of (very) small tips due to the viscosity of PDMS • PDMS to SiO2 bonding