NIH K Awards

1. NIH K Awards Office of Proposal Development Phyllis McBride, Ph.D. p-mcbride@tamu.edu April 21, 2006

2. Office of Proposal Development • Unit of the Vice President for Research • Supports faculty in the development and writing of research and educational proposals • Center-level initiatives • Multi-disciplinary research teams • Research affinity groups • Junior faculty research • Diversity in the research enterprise

3. OPD Web Page • Located at http://opd.tamu.edu/ • Serves as an interactive tool and faculty resource for the development and writing of competitive research and educational proposals to federal agencies and foundations • Includes information on: • Funding opportunities • Junior faculty support • Proposal development resources • Grant writing seminars and workshops • Grant writing workbooks and toolkits • PI perspectives on competitive proposals

4. OPD Staff • Jean Ann Bowman: jbowman@tamu.edu • Ecological and environmental sciences; agriculture-related proposals and centers • Libby Childress: libbyc@tamu.edu • Scheduling, resources, training workshop management, project coordination • Mike Cronan: mikecronan@tamu.edu • Center-level proposals, A&M System partnerships, new proposal and training initiatives • Lucy Deckard: l-deckard@tamu.edu • New faculty initiative, fellowships, physical science-related proposals, equipment and instrumentation, interdisciplinary materials group, OPD web management • Phyllis McBride: p-mcbride@tamu.edu • Craft of proposal writing training, NIH and related agency initiatives in the biomedical, social, and behavioral sciences; editing and rewriting • Robyn Pearson: rlpearson@tamu.edu • Education, liberal arts, social and behavioral sciences, and humanities-related proposals; support for interdisciplinary research group development; educational proposals; editing and rewriting

5. Panelists • Garry Adams • Professor and Associate Dean of Research, Veterinary Pathobiology • Helene Andrews-Polymenis • Assistant Professor, Microbial and Molecular Pathogenesis • David Carlson • VP for Research and Graduate Studies, HSC • Glen Laine • Director, Michael E. DeBakey Institute, Department Head and Professor, Veterinary Physiology and Pharmacology • Sara Lawhon • Postdoctoral Research Associate, Veterinary Pathobiology • Kasi Russell • Assistant Research Scientist, Veterinary Pathobiology

6. NIH History • Created in 1887 as a one-room laboratory • Now considered one of the world’s foremost research entities • Serves as a steward for medical and behavioral research for the nation

7. NIH Organization • National Institutes of Health • Office of the Director • 20 Institutes • 7 Centers • All institutes and centers work together as an integrated research network • But, each institute and center also has its own specific mission and research agenda

8. NIH Mission • To uncover new knowledge that will lead to better health for everyone • Basic scientific research in pursuit of fundamental knowledge about the nature and behavior of living systems • Applied scientific research to extend healthy life and reduce the burdens of illness and disability

9. NIH Extramural Research • Supports mission by funding research in: • Causes, diagnosis, prevention, and cure of human diseases • Processes of human growth and development • Biological effects of environmental contaminants • Understanding of mental, addictive and physical disorders • Directing programs for the collection, dissemination, and exchange of information in medicine and health, including the development and support of medical libraries and the training of medical librarians and other health information specialists.

10. FY 2007:NIH Budget and Funding Priorities • Budget • $28.6 billion • Funding priorities • Genes, environment, and health • Biodefense • Pandemic influenza • NIH roadmap for medical research • Clinical research translation • New investigators

11. Identify NIH Funding Mechanisms • NIH funding mechanisms page • http://grants.nih.gov/grants/funding/funding_program.htm • Funding mechanism • Refers to the kind of research activity that can be funded • NIH supports numerous funding mechanisms • F series Fellowships • K series Career awards • L series Loan repayment programs • P series Program projects and centers • R series Research projects • T series Training programs • Important to note that not all institutes support all funding mechanisms

12. NIH Funding Mechanisms • National Research Service Awards (NRSA) • F30 Predoctoral Awards for MD/PhD Fellowships • F31 Predoctoral Fellowships • F32 Postdoctoral Fellowships • K Awards • K01 Mentored Research Scientist Development Award • K08 Mentored Clinical Scientist Development Award • K23 Mentored Patient-Oriented Research Career Development Award • K99/00 Pathway to Independence Award New!

13. NIH NRSA F30 • Predoctoral Awards for MD/PhD Fellowships

14. NIH NRSA F31 • Predoctoral Fellowships

15. NIH NRSA F32 • Postdoctoral Fellowships

16. NIH K01 • Mentored Research Scientist Development Award

17. NIH K08 • Mentored Clinical Scientist Development Award • Investment in the development of outstanding clinician researchers. The clinician undertakes specialized study on a research topic that has intrinsic research importance and sufficient scope for learning the methodology, theories, and concepts needed for research independence. This mentored award supports specialized study for a three-, four-, or five-year period. In most cases, this is for lab or bench research.

18. NIH K23 • Mentored Patient-Oriented Research Career Development • Encourages the career development of investigators who will focus their patient-oriented research in an area involving mechanisms of human disease, therapeutic interventions, clinical trials, or development of new technologies.

19. NIH K99/00 • Pathway to Independence Award

20. Identify NIH Grant Cycles • NIH submission dates/deadlines page • http://grants.nih.gov/grants/dates.htm • Three grant cycles per calendar year • Deadlines vary according to funding mechanism • Grant cycles for K awards: • February 1 • June 1 • October 1 • Grant cycles for NRSA awards: • April 5 • August 5 • December 5

21. Identify Projects Already Funded by NIH • CRISP online database • http://crisp.cit.nih.gov/ • Includes abstracts of all projects that have already been funded by all Public Health Service agencies • National Institutes of Health • Agency for Healthcare Research and Quality • Centers for Disease Control and Prevention • Food and Drug Administration • Health Resources and Services Administration • Office of the Assistant Secretary of Health • Substance Abuse and Mental Health Services Administration

22. Search the CRISP Database

23. Know the NIH Review Criteria • Investigator • Environment • Significance • Approach • Innovation

24. Understand the NIH Review Process • Center for Scientific Review • http://cms.csr.nih.gov/ • Describes the peer review process • Offers a video of a mock review session • Provides a list of study section rosters

25. Write for Reviewers • Reviewers are: • Smart • Accomplished • Dedicated • Fair

26. Write for Reviewers • Reviewers are also: • Busy • Overworked • Tired • Skeptical • May not be as knowledgeable about the details of the proposed topic as the PI is

27. Write for Reviewers • Read the application instructions • Write material that never assumes reviewers will know what you mean • Refer to the literature thoroughly and thoughtfully • Explicitly state the rationale of the proposed investigation • Include well-designed figures and tables in the text • Present the reviewers with an organized, lucid write-up

28. Helpful Links • NIH funding opportunities page • http://grants1.nih.gov/grants/guide/index.html • Grants.gov funding opportunities page • http://www.grants.gov/search/agency.do • NIH grants tutorials • http://www.niaid.nih.gov/ncn/grants/default.htm • Grant Application Basics • How to Plan a Grant Application • How to Write a Grant Application • How to Manage Your Grant Award • Advice on Research Training and Career Awards • Annotated R01 Grant Application

29. Questions and Panel Discussion • Garry Adams • Professor and Associate Dean of Research, Veterinary Pathobiology • Helene Andrews-Polymenis • Assistant Professor, Microbial and Molecular Pathogenesis • David Carlson • VP for Research and Graduate Studies, HSC • Glen Laine • Director, Michael E. DeBakey Institute, Department Head and Professor, Veterinary Physiology and Pharmacology • Sara Lawhon • Postdoctoral Research Associate, Veterinary Pathobiology • Kasi Russell • Assistant Research Scientist, Veterinary Pathobiology