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SPECTRAL DETECTION OF NONLINEAR RF INTERACTIONS IN BIOLOGICAL PREPARATIONS EXPOSED TO RF ENERGY

SPECTRAL DETECTION OF NONLINEAR RF INTERACTIONS IN BIOLOGICAL PREPARATIONS EXPOSED TO RF ENERGY. Quirino Balzano and Christopher C. Davis Department of Electrical and Computer Engineering. RATIONALE. EXPECTED SENSITIVITY.

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SPECTRAL DETECTION OF NONLINEAR RF INTERACTIONS IN BIOLOGICAL PREPARATIONS EXPOSED TO RF ENERGY

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  1. SPECTRAL DETECTION OF NONLINEAR RF INTERACTIONS IN BIOLOGICAL PREPARATIONS EXPOSED TO RF ENERGY Quirino Balzano and Christopher C. Davis Department of Electrical and Computer Engineering RATIONALE EXPECTED SENSITIVITY • Cellular systems have been reported to apparently demodulate an RF carrier and exhibit low frequency bioeffects • If this occurs then cellular response is nonlinear • This nonlinearity should also be manifest through harmonic mixing • At 1800 MHz 10-30V/10dBm or 10-100 photons/cell/second with 106 cells in the bio-sample • The cavity is detuned by the loss in the biological preparation • Maximum sensitivity is a balance between the sample size and the cavity Q factor INSTRUMENTATION DIFFICULT TASKS • Proper calibration of nonlinearilty • Keeping nonlinearities below detectable levels with no bio-sample • Avoiding contact oxidation • Removable cavity top or bottom without compromising the Q factor • Correct location of the bio-sample in the cavity for maximum Q at 1800MHz EXPECTED OPERATING PARAMETERS • Commercial cavity filters (2 or 3) • Q  500 –1000.. • Main cavity Q=30-40x103 (unloaded) • Small bio-sample V<<1cm3 to keep main cavity tuned with high Q • Loaded main cavity Q  4x103 • Generator frequency 900 MHz • 10 mW power • Stable and clean RF generators • Cavity pass band filters (2 or 3) • 30dB low noise amplifier and spectrum analyzer • Main cavity with bio-preparation • Nonlinear device for calibration • Linear materials for bio-support structure • Combiner plus matching circulator This research is sponsored by MTHR (Mobile Telephone Health Research London, UK)

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