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EACH PATIENT - AN OPEN BOOK Interesting Clinical Cases. Dr. R.V.S.N.Sarma., M.D., M.Sc., (Canada) 5 Jayanagar, Tiruvallur 602 001 Mobile 93805 21221 Visit us at : www.drsarma.in. Clinical Problem. Middle aged lady Obesity Depression What was wrong ?
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EACH PATIENT - AN OPEN BOOKInteresting Clinical Cases Dr. R.V.S.N.Sarma., M.D., M.Sc., (Canada) 5 Jayanagar, Tiruvallur 602 001 Mobile 93805 21221 Visit us at : www.drsarma.in www.drsarma.in
Clinical Problem • Middle aged lady • Obesity • Depression • What was wrong ? • How she was investigated ? • What was the outcome ? www.drsarma.in
Clinical Presentation 48 year lady 80 kg weight Lack of interest Lethargic, Indolent MDD score high Clinically Hypothyroid Investigations TSH very high > 100 T3, T4 and FT4 very low LDL 171 mg TC 267 mg Eltroxin 50 – 300 mcg Atorvastatin 10 mg Summary of the evaluations www.drsarma.in
Follow up 49 year lady 61.9 kg weight Normal and active Anaemia improved No depression signs Clinically Euthyroid Investigations TSH ↓ (over corrected) FT4 and FT3 not done LDL 85 mg TC 168 mg HB 12 g % ECG N – HR 88/mt ↓ Eltroxin to 200 mcg Stop Atorvastatin How is she today ? www.drsarma.in
What are the messages ? • Hypothyroidism is an under current • Unless suspected we will sure miss it • Depression and hypothyroid are associated • Pregnant / Middle aged women and • Obese individuals need thyroid evaluation • ↑ in LDL and TC may predispose for IHD • Start low and Go slow, TSH for follow up www.drsarma.in