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GWAS- eQTL signal colocalisation methods

GWAS- eQTL signal colocalisation methods. Integrating GWASs and eQTL studies can elucidate mechanism of non-coding variants on diseases Challenging due to the uncertainty induced by ( i ) LD and (ii) allelic heterogeneity. Allen et al , 2017. Same causal variant(s) or not?.

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1 causal variant - PowerPoint PPT Presentation

GWAS- eQTL signal colocalisation methods