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50 maximal effect measure - PowerPoint PPT Presentation

Kd or IC50: concentration that gives 50% maximal binding; measure

TYPICAL BINDING CURVE. Maximum Number of receptors. SPECIFIC BINDING (NUMBER OF RECEPTORS OCCUPIED). Kd. Concentration of Drug Used. Kd or IC50: concentration that gives 50% maximal binding; measure of AFFINITY of the drug for the receptor. efficacy. ED50.

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50 maximal effect measure - PowerPoint PPT Presentation

Kd or IC50: concentration that gives 50% maximal binding; measure