'8 dna glcosylases' presentation slideshows

8 dna glcosylases - PowerPoint PPT Presentation

Oxidative Damage of DNA

Oxidative Damage of DNA

Oxidative Damage of DNA. Oxidative damage results from aerobic metabolism, environmental toxins, activated macrophages, and signaling molecules (NO). Compartmentation limits oxidative DNA damage. Oxidation of Guanine Forms 8-Oxoguanine. The most common mutagenic base lesion is 8-oxoguanine.

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393 views • 38 slides
Oxidative Damage of DNA

Oxidative Damage of DNA

Oxidative Damage of DNA. Oxidative damage results from aerobic metabolism, environmental toxins, activated macrophages, and signaling molecules (NO). Compartmentation limits oxidative DNA damage. Oxidation of Guanine Forms 8-Oxoguanine. The most common mutagenic base lesion is 8-oxoguanine.

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493 views • 34 slides
Oxidative Damage of DNA

Oxidative Damage of DNA

Oxidative Damage of DNA. Oxidative damage results from aerobic metabolism, environmental toxins, activated macrophages, and signaling molecules (NO). Compartmentation limits oxidative DNA damage. Oxidation of Guanine Forms 8-Oxoguanine. The most common mutagenic base lesion is 8-oxoguanine.

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430 views • 34 slides
Oxidative Damage of DNA

Oxidative Damage of DNA

Oxidative Damage of DNA. Oxidative damage results from aerobic metabolism, environmental toxins, activated macrophages, and signaling molecules (NO). Compartmentation limits oxidative DNA damage. Oxidation of Guanine Forms 8-Oxoguanine. The most common mutagenic base lesion is 8-oxoguanine.

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354 views • 34 slides
from Marnett and Plastaras, Trends Genet . 17 , 214 (2001)

from Marnett and Plastaras, Trends Genet . 17 , 214 (2001)

Endogenous DNA Damage. from Marnett and Plastaras, Trends Genet . 17 , 214 (2001). Biological Molecules are Labile. RNA is susceptible to hydrolysis. Reduction of ribose to deoxyribose gives DNA greater stability. N-glycosyl bond of DNA is more labile.

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324 views • 31 slides
Oxidative Damage of DNA

Oxidative Damage of DNA

Oxidative Damage of DNA. Oxidative damage results from aerobic metabolism, environmental toxins, activated macrophages, and signaling molecules (NO). Compartmentation limits oxidative DNA damage. Oxidation of Guanine Forms 8-Oxoguanine. The most common mutagenic base lesion is 8-oxoguanine.

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556 views • 30 slides
from Marnett and Plastaras, Trends Genet . 17 , 214 (2001)

from Marnett and Plastaras, Trends Genet . 17 , 214 (2001)

Endogenous DNA Damage. from Marnett and Plastaras, Trends Genet . 17 , 214 (2001). Biological Molecules are Labile. RNA is susceptible to hydrolysis. Reduction of ribose to deoxyribose gives DNA greater stability. N-glycosyl bond of DNA is more labile.

★ ★ ★ ★ ★

432 views • 30 slides
Oxidative Damage of DNA

Oxidative Damage of DNA

Oxidative Damage of DNA. Oxidative damage results from aerobic metabolism, environmental toxins, activated macrophages, and signaling molecules (NO). Compartmentation limits oxidative DNA damage. Oxidation of Guanine Forms 8-Oxoguanine. The most common mutagenic base lesion is 8-oxoguanine.

★ ★ ★ ★ ★

403 views • 30 slides
Oxidative Damage of DNA

Oxidative Damage of DNA

Oxidative Damage of DNA. Oxidative damage results from aerobic metabolism, environmental toxins, activated macrophages, and signaling molecules (NO). Compartmentation limits oxidative DNA damage. Oxidation of Guanine Forms 8-Oxoguanine. The most common mutagenic base lesion is 8-oxoguanine.

★ ★ ★ ★ ★

345 views • 30 slides

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