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Chap. 2 Antibody Engineering: Design for Specific Applications

Chap. 2 Antibody Engineering: Design for Specific Applications

Chap. 2 Antibody Engineering: Design for Specific Applications Factors need to be considered in the design of Ab molecules Specificity and affinity of the binding site Valency of Ab Sizes Requirement for effector function Attachment of therapeutic effector or reporter molecules

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644 views • 27 slides
Chap. 2 Antibody Engineering: Design for Specific Applications

Chap. 2 Antibody Engineering: Design for Specific Applications

Chap. 2 Antibody Engineering: Design for Specific Applications Factors need to be considered in the design of Ab molecules Specificity and affinity of the binding site Valency of Ab Sizes Requirement for effector function Attachment of therapeutic effector or reporter molecules

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395 views • 26 slides
UCSC Known Genes Version 3 Take 9

UCSC Known Genes Version 3 Take 9

UCSC Known Genes Version 3 Take 9. Known Gene History. Initially based on Genie predictions constrained by BLAT mRNA alignments. David Kulp got busy at Affy. Switched to RefSeq Jim got paranoid Riken RNAs would take over Fan built KG 1 Mark got annoyed at low quality predictions

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320 views • 21 slides
Chap. 5 Production of Monoclonal Antibodies Introduction

Chap. 5 Production of Monoclonal Antibodies Introduction

Chap. 5 Production of Monoclonal Antibodies Introduction Expression and Purification of Mab in an economically viable manner a) production system requirement i. form of Ab required ii. applications --- scale of production specification of Ab purification

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438 views • 20 slides

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