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Probing the Genome with scFISH

Probing the Genome with scFISH

Sequence-based In Situ Detection of Chromosomal Abnormalities at High Resolution -. Probing the Genome with scFISH. Joan HM Knoll, PhD, FACMG, FCCMG University of Missouri-Kansas City School of Medicine. The Paradigm. Prenatal, postnatal and neoplastic chromosomal abnormalities

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646 views • 53 slides
Fluorescent In Situ Hybridization

Fluorescent In Situ Hybridization

Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors. This technique is useful for identifying chromosomal abnormalities, gene mapping, characterizing somatic cell hybrids, checking amplified genes and studying the mechanism of rearrangements. RNA FISH is used to measure and localize mRNAs and other transcripts within tissue sections or whole mounts. https://www.creative-bioarray.com/services/Fluorescent-In-Situ-hybridization-FISH.htm

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335 views • 16 slides
fluorescent in situ hybridization

fluorescent in situ hybridization

Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors. This technique is useful for identifying chromosomal abnormalities, gene mapping, characterizing somatic cell hybrids, checking amplified genes and studying the mechanism of rearrangements. RNA FISH is used to measure and localize mRNAs and other transcripts within tissue sections or whole mounts. https://www.creative-bioarray.com/services/Fluorescent-In-Situ-hybridization-FISH.htm

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1.07k views • 16 slides

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