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Dna polymerase structure - PowerPoint PPT Presentation

Lecture 1:

Lecture 1:. DNA Polymerase and the Replication Fork. Use of biochemistry (assays) and genetics (mutant phenotypes) to define function. Fidelity/Specificity: bioregulation through substrate control of molecular choice. Using both Biochemistry and Genetics to understand function.

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Using both Biochemistry and Genetics to understand function

Using both Biochemistry and Genetics to understand function. DNA Replication: The Task and Challenge. Semiconservative Duplication. Speed : very rapid duplication of every nucleotide. (ex: 6 x 10 9 bp in 8 hrs in humans). Fidelity : extremely low error rate.

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Dna polymerase structure - PowerPoint PPT Presentation

Lecture 1:

Using both Biochemistry and Genetics to understand function