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Ich gcp principles 3 - PowerPoint PPT Presentation

Complexity of the insulin signaling pathway

IRS1. IRS2. IRS3. p85 ?. p110 ?. p55 ?. IRS4. p110 ?. p50 ?. p110 ?. p85 ?. p55 ?. Complexity of the insulin signaling pathway. Insulin. TNF ?. Cytokines. IGF1. Plasma membrane. TNFR. Rec. IGF1R. PTP1B. CAP. Shc. Jak. cbl. Jnk. Rac. cdc42. Stat. ?. ?. PTEN. PDK 1,2.

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Ich gcp principles 3 - PowerPoint PPT Presentation

Complexity of the insulin signaling pathway