Mechanisms of immune evasion by Trypanosoma brucei
Trypanosoma brucei is the parasite responsible of causing both human (sleeping sickness) and animal (nagana) African trypanosomiasis, diseases of medical and veterinary importance. The infection in cattle has a major impact on African economy, which limits the production of milk and meat. The life cycle of these parasites extracellular alternate between the salivary glands of the insect transmitter (tsetse fly) and the blood of the vertebrate (mammal), presenting different morphological stages: procyclic, epimastigote, metacyclic forms in the invertebrate, long-slender trypomastigotes and shortstumpy forms in the vertebrate.
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