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Substituents and Bio-isosteres in Medicinal Chemistry

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4. Structural Effects on Reactivity

4. Structural Effects on Reactivity. 4.1 Electronic Effects: 4.1.1 Inductive and field effects 4.1.2 Resonance effect 4.2 Steric Effects 4.2.1 Steric hindrance 4.2.2 Strain 4.2.3 Stereo electronic effect 4.3 Linear Free Energy Relationships 4.3.1 Hammett equation

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Mesomeric effect - PowerPoint PPT Presentation

Substituents and Bio-isosteres in Medicinal Chemistry

4. Structural Effects on Reactivity