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Side-effects and Potential Risks for CART Cell Therapy

Side-effects and Potential Risks for CART Cell Therapy

Chimeric antigen receptor (CAR) is a recombinant immunoreceptor combining an antibody-derived targeting fragment with signaling domains capable of activating cells, which endows T cells with the ability to recognize tumor-associated surface antigens independent of the expression of major histocompatibility complex (MHC) Molecules. Despite the promising therapeutic effects of CAR T therapy, there still has several several-sided that needs to get through.

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318 views • 10 slides
A Brief Introduction of CD19 CAR-T Therapy

A Brief Introduction of CD19 CAR-T Therapy

The CD19 chimeric antigen receptors (CARs) are fusion proteins expressed on the surface of T cells by gene recombination technology, which combines a hinge region, a transmembrane domain, and one or more intracellular T cells that will specifically recognize the single-chain variable region and the extracellular domain of antibodies of CD19 by stimulating or co-stimulatory molecules. Learn more about CAR T at https://www.creative-biolabs.com/car-t/form/car-t-clinical-trial-review.aspx

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367 views • 9 slides
hybridoma cells

hybridoma cells

As a super provider of diverse antibodies, Creative Biolabs offers customers several approaches for scFv generation such as one-stop solution for developing CAR from Hybridoma, which is a very mature and useful technology for scFv construction. Learn more from https://www.creative-biolabs.com/car-t/scfv-generation-from-hybridoma-cells.htm

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39 views • 2 slides

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