'P450' presentation slideshows

Biotransformation of Xenobiotics

Biotransformation of Xenobiotics. Overview. Phase I and Phase II enzymes Reaction mechanisms, substrates Enzyme inhibitors and inducers Genetic polymorphism Detoxification Metabolic activation. Introduction. Purpose Converts lipophilic to hydrophilic compounds Facilitates excretion

1.06k views • 64 slides

Biotransformation of Xenobiotics

Biotransformation of Xenobiotics. Overview. Phase I and Phase II enzymes Reaction mechanisms, substrates Enzyme inhibitors and inducers Genetic polymorphism Detoxification Metabolic activation. Introduction. Purpose Converts lipophilic to hydrophilic compounds Facilitates excretion

867 views • 55 slides

Cytochrome P450

Cytochrome P450. Lecture 8 Modified from textbooks, journals and internet sources. Introduction. Cytochrome P450 (P450) ? very large and diverse superfamily of hemoproteins range of proteins found in all domains of life

1.48k views • 34 slides

Cytochrome P450

Cytochrome P450. Lecture 8 Modified from textbooks, journals and internet sources. Introduction. Cytochrome P450 (P450) ? very large and diverse superfamily of hemoproteins range of proteins found in all domains of life

959 views • 34 slides

Drug/ xenobiotic metabolism and pharmacogenetics

850 views • 24 slides

Revise the intent of drug metabolism and its different phases.

6: cytochrome system & drug metabolism. objectives. Revise the intent of drug metabolism and its different phases. Define the role of cytochrome system in relation to drug metabolism . Expand on the nature, location, nomenclature, structure, distribution & function of CYT P450 .

163 views • 15 slides

Cytochrome P450 (Cyp450)

528 views • 12 slides