'Pdk 1 substrates' presentation slideshows

PDK-1 Signaling Pathway

As a member of AGC kinases family, PDK-1, a protein of 556 amino acids, is composed of serine and threonine kinases. The catalytic domain of these serine and threonine kinases show a sequential similarity with cAMP-dependent protein kinase 1 (PKA), cGMP-dependent protein kinase (PKG) and protein kinase C (PKC). There are two phosphorylation sites that many AGC kinases and they are to regulate the activity of AGC kinases.

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