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Negative regulation of immune responses by various mechanisms

Negative regulation of immune responses by various mechanisms. ITAM-ITIM. ITIM- mediated inhibition ITIM recruited phosphatases inhibit the ITAM-induced kinase cascade. B cell regulation CD22. Sialic acid. B cell regulation Fc ? RIIb. Fc ? RII mediated B cell feedback regulation. Ag.

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DIFFERENTIATION AND MATURATION OF T CELLS IN THE THYMUS

DIFFERENTIATION AND MATURATION OF T CELLS IN THE THYMUS. The cellular organization of the thymus. The proportion of the thymus that produces T cells decreases with age. Commitment to the T-cell lineage changes receptor expression. Lack of IL7 signaling (IL7 or IL7R) stalls

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392 views • 18 slides

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Peptide tcr - PowerPoint PPT Presentation

Negative regulation of immune responses by various mechanisms

DIFFERENTIATION AND MATURATION OF T CELLS IN THE THYMUS