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Chromosomal Abnormalities II SDK October 28, 2013

Chromosomal Abnormalities II SDK October 28, 2013

Chromosomal Abnormalities II SDK October 28, 2013. II- STRUCTURAL CHROMOSOMAL ABNORMALITIES. II- STRUCTURAL ABNORMALITIES. Theses are group of problems that is caused by the structural abnormalities of the chromosomes. Structural abnormalities may be Balanced or unbalanced

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1.25k views • 83 slides
Chromosome aberrations in HAEMATOLOGIC MALIGNANCIES

Chromosome aberrations in HAEMATOLOGIC MALIGNANCIES

Chromosome aberrations in HAEMATOLOGIC MALIGNANCIES. Increased growth Blockage of differentiation Less apoptosis. Haematological malignancies. HAEMATOLOGIC MALIGNANCIES MAY BE CLASSIFIED BY:. 1. CLINICAL COURSE : acute leukaemias or chronic leukaemias 2. LINEAGE : lymphoid lineage

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878 views • 56 slides
Normal haemopoiesis

Normal haemopoiesis

Normal haemopoiesis. ABNORMALITIES IN THE HEMOPOIETIC SYSTEM. CAN LEAD TO HEMOGLOBINOPATHIES HEMOPHILIA DEFECTS IN HEMOSTASIS/THROMBOSIS HEMATOLOGICAL MALIGNANCY. MUTATIONS AND DNA. VARIOUS TYPES OF MUTATIONS CAN OCCUR LEADING TO DISEASE PHENOTYPE POINT MUTATIONS INSERTIONS OR DELETIONS

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569 views • 43 slides
Chronic myeloid leukemia

Chronic myeloid leukemia

Chronic myeloid leukemia. The myeloproliferative diseases (MPDs) are clonal stem cell disorders characterised by leukocytosis, thrombocytosis, erythrocytosis, splenomegaly, and bone marrow hypercelularity

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804 views • 39 slides
Lymphoblastic Leukemia Clinical and Laboratory Findings

Lymphoblastic Leukemia Clinical and Laboratory Findings

Lymphoblastic Leukemia Clinical and Laboratory Findings. Jason Corbeill PA-C Lock Haven University. Leukemia. Results from the acquired somatic mutation of a chromosome leading to proliferation of a hematopoietic progenitor cell clone. Leukemia. May be either acute or chronic

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732 views • 34 slides

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