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DNA-PK Signaling Pathway

The DNA-dependent protein kinase (DNAu2013PK) is a nuclear serine/threonine protein kinase which is activated after the interaction with its target DNA. DNAu2013PK is a complex composed of a large catalytic subunit named DNAu2013PKcs and a heterodimer of Ku proteins (Ku70/80) that is a regulatory factor.

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DNA-PK Signaling Pathway