'Rx control developmental strategy' presentation slideshows

Rx control developmental strategy - PowerPoint PPT Presentation

Using Genomics in Clinical Trial Design

Using Genomics in Clinical Trial Design

Using Genomics in Clinical Trial Design. Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://linus.nci.nih.gov. BRB Website http://linus.nci.nih.gov/brb. Powerpoint presentations and audio files Reprints & Technical Reports BRB-ArrayTools software

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1.03k views • 62 slides
Targeted (Enrichment) Design

Targeted (Enrichment) Design

Targeted (Enrichment) Design. Prospective Co-Development of Drugs and Companion Diagnostics. Develop a completely specified genomic classifier of the patients likely to benefit from a new drug Pre-clinical, phase II data, archived specimens from previous phase III studies

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844 views • 62 slides
Some Statistical Aspects of Predictive Medicine

Some Statistical Aspects of Predictive Medicine

Some Statistical Aspects of Predictive Medicine. Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://brb.nci.nih.gov. Biometric Research Branch Website http://brb.nci.nih.gov. Powerpoint presentations Reprints BRB-ArrayTools software

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910 views • 52 slides
Moving from Correlative Studies to Predictive Medicine

Moving from Correlative Studies to Predictive Medicine

Moving from Correlative Studies to Predictive Medicine. Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute brb.nci.nih.gov. Disclosure Information Richard Simon, D.Sc. I have no financial relationships to disclose.

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930 views • 52 slides
Statistical Issues in the Evaluation of Predictive Biomarkers

Statistical Issues in the Evaluation of Predictive Biomarkers

Statistical Issues in the Evaluation of Predictive Biomarkers. Richard Simon, D.Sc. Chief, Biometric Research Branch National Cancer Institute http://brb.nci.nih.gov. Kinds of Biomarkers. Surrogate endpoint Pre & post rx, early measure of clinical outcome Pharmacodynamic

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703 views • 33 slides

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