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Inhibition of the mTOR and MAPK pathways in the treatment of osteosarcoma

Inhibition of the mTOR and MAPK pathways in the treatment of osteosarcoma

Inhibition of the mTOR and MAPK pathways in the treatment of osteosarcoma. Kathleen M. Diehl, M.D. FACS Assistant Professor University of Michigan. Background. Osteosarcoma cell lines SAOS-2, COL, OS-187 Rapamycin Sirolimus Natural macrolide antibiotic (anti-fungal)

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365 views • 21 slides
Inhibition of the mTOR and MAPK pathways in the treatment of osteosarcoma

Inhibition of the mTOR and MAPK pathways in the treatment of osteosarcoma

Inhibition of the mTOR and MAPK pathways in the treatment of osteosarcoma. Kathleen M. Diehl, M.D. FACS Assistant Professor University of Michigan. Background. Osteosarcoma cell lines SAOS-2, COL, OS-187 Rapamycin Sirolimus Natural macrolide antibiotic (anti-fungal)

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363 views • 21 slides
Supplementary Figure 1

Supplementary Figure 1

catalase. p53. MW(kDa). 170. 130. catalase. 95. PIG3. MW(kDa). 72. 55. 72. 43. 55. 34. 43. 34. 26. Supplementary Figure 1. A. B. Vector PIG3. ??. 160. ??. ??. 140. 120. 100. DCF fluorescence level. 80. 60. 40. 20. 0. H1299. SW480. HCT116 p53 -/-.

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259 views • 13 slides
Supplementary Figure 1

Supplementary Figure 1

catalase. p53. MW(kDa). 170. 130. catalase. 95. PIG3. MW(kDa). 72. 55. 72. 43. 55. 34. 43. 34. 26. Supplementary Figure 1. A. B. Vector PIG3. ??. 160. ??. ??. 140. 120. 100. DCF fluorescence level. 80. 60. 40. 20. 0. H1299. SW480. HCT116 p53 -/-.

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150 views • 13 slides
Poster Discussion 2 - Biology

Poster Discussion 2 - Biology

Poster Discussion 2 - Biology. Genome Transcriptome Proteome Metastasome. Genome. 39267: HDAC inhibitor/multidrug resistant cell lines PCI-24781 induces acetylation, inhibits growth, enhances chemosensitivity 39309: EXT /osteochondromas

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192 views • 10 slides
Poster Discussion 2 - Biology

Poster Discussion 2 - Biology

Poster Discussion 2 - Biology. Genome Transcriptome Proteome Metastasome. Genome. 39267: HDAC inhibitor/multidrug resistant cell lines PCI-24781 induces acetylation, inhibits growth, enhances chemosensitivity 39309: EXT /osteochondromas

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209 views • 10 slides

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