'Situ hybridization fish' presentation slideshows

Molecular cytogenetics

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Fluorescent In Situ Hybridization

Fluorescence in situ hybridization (FISH), developed in 1980s, is a cytogenetic technique using fluorescent probes to bind the chromosome with a high degree of complementarity. It is a powerful and easy method to detect RNA or DNA sequences in cells, tissues and tumors. This technique is useful for identifying chromosomal abnormalities, gene mapping, characterizing somatic cell hybrids, checking amplified genes and studying the mechanism of rearrangements. RNA FISH is used to measure and localize mRNAs and other transcripts within tissue sections or whole mounts.

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Molecular Cytogenetics Market 2018 To Post-Huge Revenue In The Near Future 2026

High prevalence of cancer and increasing application of molecular biology in detection of inherited susceptibilities associated with cancer development is expected to boost this Market

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ISH and FISH

In situ Hybridization (ISH) is a method that allows to localize and detect nucleic acid sequences within structurally intact cells or morphologically preserved tissues sections. Fluorescence in situ hybridization (FISH) is a kind of ISH which uses fluorescent probes binding parts of the chromosome to show a high degree of sequence complementarity.

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