'Synonymous' presentation slideshows

686 views • 53 slides

Tutorial #2

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Significance of variation

Significance of variation. McDonald and Kreitman 1991. Mutations are the raw material of evolution Source of new alleles Source of new genes Produce heritable variation that is transmitted across generations Small-scale mutations Macromutations Polyploidy Doubling of whole genomic DNA.

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Number of substitutions between two protein-coding genes

Number of substitutions between two protein-coding genes. Dan Graur. Handout. Computing the number of substitutions between two protein-coding sequences is more complicated, because a distinction should be made between synonymous and nonsynonymous substitutions.

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Chapter 3 Substitution Patterns

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Lecture 22: Signatures of Selection and Introduction to Linkage Disequilibrium

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Human survivorship

Human survivorship. Developed. Bob May (2007), TREE 22: 497-503. Developing. Liverpool 150 years ago. Today. 1860. Evolution of infectious disease #1 Evolution of the MHC. Steve Paterson rm 202, s.paterson@liv.ac.uk. Map of MHC. Map of MHC. presentation of peptides by MHC.

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Mutation

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The influence of population size on patterns of natural selection in mammals

The influence of population size on patterns of natural selection in mammals. Carolin Kosiol < kosiol@cornell.edu > Cornell University 21 st December 2007 Isaac Newton Institute. 0.05. human. chimp. macaque. mouse. rat. dog. Six Mammalian Genomes.

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The influence of population size on patterns of natural selection in mammals

The influence of population size on patterns of natural selection in mammals. Carolin Kosiol < kosiol@cornell.edu > Cornell University 21 st December 2007 Isaac Newton Institute. 0.05. human. chimp. macaque. mouse. rat. dog. Six Mammalian Genomes.

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The influence of population size on patterns of natural selection in mammals

The influence of population size on patterns of natural selection in mammals. Carolin Kosiol < kosiol@cornell.edu > Cornell University 21 st December 2007 Isaac Newton Institute. 0.05. human. chimp. macaque. mouse. rat. dog. Six Mammalian Genomes.

200 views • 18 slides

Changes in DNA

Changes in DNA. Analogy. We will be using a sentence as an analogy to represent a strand of DNA. Our sentence is: The fat cat ate the wee rat. If this sentence represents a strand of DNA, what does each word represent? What does each letter represent?. Mutations?!?.

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Lab 11 :Test of Neutrality and Evidence for Selection

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Michael Pina, Salomon Garcia Journal Club Presentation BIOL398-01/S10: Bioinformatics Laboratory

Patterns of selection for or against amino acid change among different CD4 T-cell count progressor groups. Michael Pina, Salomon Garcia Journal Club Presentation BIOL398-01/S10: Bioinformatics Laboratory March 2, 2010. Outline. Introduction to the Markham et al. paper

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ICB 2007, Hong Kong Supplementary formulas Rates of Evolutionary Changes

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Regionalisms, Slang and Strine: Australian Slang by Region.

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Isopropyl Alcohol - IPA 99.5% (4x1 Gallon)

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54 views • 1 slides