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Determining the Charge on a Peptide

Determining the Charge on a Peptide. Peptide. Given the peptide: Leu-Lys-Tyr-Glu Problem: Determine the net charge on this peptide at a given pH. First: Look up and assign pKa values to each ionizable group. (You may want to draw out the structure for the peptide.). Structure and pKa values.

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Third ionizations - PowerPoint PPT Presentation

Determining the Charge on a Peptide