'Totally unbound fu 1' presentation slideshows

Since drugs can bind with proteins their distribution volume in the body can be

Since drugs can bind with proteins their distribution volume in the body can be Affected by their interaction with protein Drug (Cu) + Protein (Cp) ? Drug-Protein (Cb) Total drug concentration C = Cu + Cb At equilibrium then K = Cb / (Cu Cp), but Cp is basically constant

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