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TRANSDERMAL DRUG DELIVERY SYSTEM

TRANSDERMAL DRUG DELIVERY SYSTEM

TRANSDERMAL DRUG DELIVERY SYSTEM. Dr. Basavaraj K. Nanjwade M. Pharm., PhD KLE University College of Pharmacy BELGAUM-590010, Karnataka, India. E-mail: nanjwadebk@gmail.com Cell No: 00919742431000. CONTENTS. Introduction Objectives of TDDS Advantages & disadvantages

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5.33k views • 122 slides
Pharmacokinetics WebQuest

Pharmacokinetics WebQuest

Pharmacokinetics WebQuest. http:// www.speedlighter.ca/2011/12/25/why-i-shoot-stills/courtney-craig-photo-by-michael-willems /. Kimberly Koon, Pharm. D. BW733 October 1, 2013. Overview. Introduction Absorption IV, SubQ , IM Oral, SL transdermal, rectal, vaginal, inhalation, topical

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462 views • 27 slides
Microwave non-destructive testing technique for characterization of HPMC-PEG 3000 films

Microwave non-destructive testing technique for characterization of HPMC-PEG 3000 films

Microwave non-destructive testing technique for characterization of HPMC-PEG 3000 films. Nor Khaizan Anuar 1,3 , Wong Tin Wui 1,3* , Mohd Nasir Taib 2,3 and Deepak K. Ghodgaonkar 4

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279 views • 18 slides
TRANSDERMAL DRUG DELIVERY SYSTEM Ms.Wajiha Iffat M.Pharm

TRANSDERMAL DRUG DELIVERY SYSTEM Ms.Wajiha Iffat M.Pharm

TRANSDERMAL DRUG DELIVERY SYSTEM Ms.Wajiha Iffat M.Pharm. DEFINITION TYPES OF TDDS FACTORS AFFECTING TDDS TDDS IN USE. Transdermal Drug Delivery System (TDDS) A self-contained, discrete dosage form It delivers a drug through intact skin at a controlled rate into the systemic circulation

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617 views • 12 slides
Improvement of Bioavailability of Valsartan through Novel Transdermal Drug Delivery System

Improvement of Bioavailability of Valsartan through Novel Transdermal Drug Delivery System

Valsartan is a potent and specific competitive angiotensin II antagonist which is used in the management of hypertension. It is well absorbed following oral administration, with rather poor bioavailability of about 25 . Peak plasma concentration of valsartan occurs 2 4 hours after ingestion. Optimized VAL SLN was prepared by pre emulsion sonication method and sprays dried to improve the handling processing and stability. Solid state studies such as Infra Red Spectroscopy and Differential Scanning Calorimetry indicated absence of any chemical interaction between valsartan and the lipids. Prepared patches possess satisfactory physiochemical characteristics. The absorption of VAL SLN patches F 4 resulted in 2.02 fold increase in bioavailability as compared to oral capsule formulation. Results of pharmacokinetic studies indicated that the solid lipid nanoparticles can be successfully used as potential vehicles for enhancement of bioavailability of poorly soluble drugs. The aim of the study was to study the enhancement of bioavailability of valsartan from transdermally applied solid lipid nanoparticles. Dr. Reena Antony "Improvement of Bioavailability of Valsartan through Novel Transdermal Drug Delivery System" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-1 | Issue-6 , October 2017, URL: https://www.ijtsrd.com/papers/ijtsrd2508.pdf Paper URL: http://www.ijtsrd.com/pharmacy/other/2508/improvement-of-bioavailability-of-valsartan-through-novel-transdermal-drug-delivery-system/dr-reena-antony

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99 views • 7 slides

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