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TNF-alpha activates osteoclasts independent of and Synergistic with RANKL

TNF-alpha activates osteoclasts independent of and Synergistic with RANKL. Susannah A. Hill. Background. Recent research has implicated RANKL as the strongest cytokine precursor of osteoclasts. Can TNF-alpha upregulate osteoclasts without RANKL?. 3 Studies. Compare TNF-alpha to RANKL

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Vivo enviornment - PowerPoint PPT Presentation

TNF-alpha activates osteoclasts independent of and Synergistic with RANKL