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Center for Stem Cell Biology & Regenerative Medicine. Faculty meeting 08/01/11. Agenda. Maryland Stem Cell Research Funding Summary Dan Gincel , Maryland MSCRF/TEDCO Stem Cell Consortium Update James Goolsby , Paragon Bioservices
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Center for Stem Cell Biology & Regenerative Medicine Faculty meeting 08/01/11
Agenda • Maryland Stem Cell Research Funding Summary • Dan Gincel, Maryland MSCRF/TEDCO • Stem Cell Consortium Update • James Goolsby, Paragon Bioservices • Mohan Vemuri and Mark Powers, Life Technologies • Overview of working groups • Curt Civin • Sarah Netzel-Arnett • Technology Updates • Bruce Yu • Scott Devine • Brief Presentations by three 2011 MSCRF Recipients • Maria Nurminskaya • Paul Yarowski • FeyruzRassool
Maryland Stem Cell Research Funding • Dan Gincel, PhD (Director, MSCRF/TEDCO, State of Maryland)
Stem Cell Center Mission • Develop and support a highly collaborative and interdisciplinary environment that promotes stem cell research • Encourage translation of discoveries into innovative and beneficial clinical applications that enhance the diagnosis, treatment and prevention of human diseases • Establish synergistic collaborations among academia, business and federal laboratories located in Maryland
Stem Cell Consortium • Services: Paragon Bioservices, BioPark • James Goolsby, PhD • Education: Life Technologies • Mohan Vemuri, PhD • Mark Powers, PhD
Technologies on Campus • Bruce Yu, PhD, Associate Professor at the Fischell Department of Bioengineering (UMCP) and School of Pharmacy (UMB) • byu@rx.umaryland.edu • Scott Devine, PhD, Associate Professor, Dept. of Medicine (Endocrinology), Institute for Genome Sciences • sdevine@som.umaryland.edu
Current Working Groups • Intestinal stem cells • Cardiovascular stem cells • Neural stem cells • Hematopoietic and cancer stem cells • Skeletal (Muscle, Cartilage, Fat and Bone) stem cells • iPSdevelopment
Goals of Working Groups • Develop collaborative research teams • Promote interactions of basic researchers in translational and clinical projects • Generate successful research projects and funding proposals by providing opportunities to present and discuss research findings and experimental proposals among a multidisciplinary team of colleagues
Expectations & Deadlines • Assign coordinator • Initial Meeting – end of August/ early Sept. • Group Proposal Update at Fall Faculty meeting • Mid-November MSCRF LOI deadline • Mock reviews (December) • January MSCRF Deadline
2011 MSCRF Recipients • Investigator Initiated • Rassool, Feyrus, “Efficacy of remodeling the DNA damage response in induced pluripotent stem cells engineered by different methods” • Exploratory • Chen, Xiaochun, “MicroRNA Regulators of ex vivo Human Hematopoietic Stem Cell Expansion” • Du, Shao Jun, “Reprogramming of satellite cells and human mesenchymal stem cells for muscle repair”
2011 MSCRF Recipients • Exploratory cont’d • Yarowski, Paul, “Stem cell therapy for traumatic brain injury” • Post doctoral Fellowship • Shanmugasundaram, Shobana, “Optimization of the 3D PLLA fiber scaffolds for osteogenic differentiation in stem cells”
Next Steps • Send MSCRF Specific aims and reviewer comments (pinksheets) to Wendy Sanders • Hold working group meetings • Fall Stem Cell Center faculty meeting • Any questions? • MiekSegers, • Tami Kingsbury, or • Curt Civin