Nachtrag Reviews / Publikationen Kapitel 1- Genetik der Rekombination, Hypermutation

Aug 11, 2023

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This review summarizes key findings from research papers on the genetics of recombination, hypermutation, and class switching, including the stable expression of immunoglobulin gene V(D)J recombinase activity, in 3T3 fibroblasts. It also explores the in vitro movement of V(D)J recombination and the hairpin opening and overhang processing by the Artemis/DNA-dependent protein kinase complex in nonhomologous end-joining and V(D)J recombination.

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Nachtrag Reviews / Publikationen Kapitel 1- Genetik der Rekombination, Hypermutation

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Nachtrag Reviews / Publikationen Kapitel 1- Genetik der Rekombination, Hypermutation und des Klassenwechsel D.G.Schatz and D.Baltimore (1988). Stable Expression of immunoglobulin gene V(D)J recombinase activity by gene transfer into 3T3 fibroblasts. Cell 53, 107-115. D.G. Schatz (1997). V(D)J recombination moves in vitro. Seminars in Immunology 9, 149-159. Y. Ma et al. (2002). Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end-joining and V(D)J recombination. Cell 108, 781-794.