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NanoSafety & NanoEthics Status/Trends/State-of-the-art

NanoSafety & NanoEthics Status/Trends/State-of-the-art. Chulalongkorn University July-October 2007. NanoSafety & NanoEthics Status/Trend/State-of-the-art. Commissioned to CU by NANOTEC 4-month study First phase of Guideline Drafting Project. Methodology. Literature Review (>200 articles)

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NanoSafety & NanoEthics Status/Trends/State-of-the-art

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  1. NanoSafety & NanoEthicsStatus/Trends/State-of-the-art Chulalongkorn University July-October 2007

  2. NanoSafety & NanoEthicsStatus/Trend/State-of-the-art • Commissioned to CU by NANOTEC • 4-month study • First phase of Guideline Drafting Project

  3. Methodology • Literature Review (>200 articles) • Participation in OECD (WPMN1, London) and APO (Korea) forums • Review of Draft Final Report by NANOTEC • Seminar • 4 Hr presentation1 Hr Q&A • Presentation to NANOTEC Executive Board

  4. Concerns for NanoSafety • Environmental • Contamination in soil, water, air • Occupational Health • Workers in nanomaterial manufacturing plants • Mostly exposure to nanomaterial dust • Consumer Protection • NanoCosmetics safety • NanoFabrics safety • Etc.

  5. Objectives of Nano Studies • Standardizednanomaterials • Parameter end points • Release • Fate • Exposure Risk Assessment Model In vitro In vivo Risk

  6. Outcome of these Studies • Trade Regulations • Voluntary Programs • Measures • Preventive measures • New manufacturing techniques • New monitoring techniques • Etc. • Handling guidelines • Recycling

  7. NonsystematicEvidence for NanoToxicity • Local inflamatory response • Translocationlung->liver & brain • Gulf-War Kidney Syndrome • Burning Semen Disease Top photo from Maynard, A. D. 2005. Nanotechnology: Overview and Relevance to Occupational Health. http://ohp.nasa.gov/disciplines/env-health/vits/2005/2005-10-21_NASA_MaynardHandout.pdf Middle and lower photo courtesy of Dr. Antonietta M. Gatti, Biomaterial Lab, U. of Modena & Reggio Emilia, Italy

  8. Systematic Approach Germany-NANOCARE • Exhaustive review of past studies • Representative set of manufactured nanomaterials to be studied (vary property parameters) • In vitro / in vivo studies • Parameter end points to be studied • Examples: NANOCARE, OECD Germany’s NANOCARE Project Japan-NEDO

  9. National Efforts • France • UK • Finland • Belgium • Germany • Switzerland http://www.nationsonline.org/maps/continents_map_sm.jpg • USA • China • Japan • Australia • New Zealand

  10. USA: trend of NSF nanobudget

  11. Regional Efforts • Information exchange • Workshops • ETPIS FP5, 6, 7, … • Risk Assessment, management, reduction

  12. International Efforts • ISO TC-229 • Terminology & Nomenclature • Metrology & Characterization • EHS • OECD • WPMN 1, 2, 3 • 6 working parties • IFCS Forum VI • NanoIssues • UNESCO • COMEST

  13. NanoEthics • Public trust in nanotechnology • Nanoresearch ethics - accountability to the public • Use of implanting nano-devices in humans • Nano-divide: the have and the have-not • Impact on developing countries • Technology assessment of nanotechnology • Social impacts of nanotechnology • Nanotechnology and privacy • Nanotechnology and the military • Nanoscience as catalyst for educational reform

  14. Cutting Edge Technologies • Nanoparticles monitoring tech • Nanoparticles filtering tech • Secure integrated industrial systems • Personal monitoring badges EU-NANOSAFE EU-NANOSAFE Representative morphology of non-nanobadges

  15. Recommendations • Global concern for nanosafety and nanoethics • Monitoring of international movement • Active participation in global forums • Local research both in nanosafety and nanoethics • Nano certificaton mark should proceed

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