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3.0. Background & Overview of Systematic Review. Definitions. A Systematic Review is “The application of procedures that limit bias in the assembly, critical appraisal, and synthesis of all relevant studies on a particular topic. Meta analysis may be but is not necessarily part of the
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3.0 Background & OverviewofSystematic Review
Definitions A Systematic Review is “The application of procedures that limit bias in the assembly, critical appraisal, and synthesis of all relevant studies on a particular topic. Meta analysis may be but is not necessarily part of the Process” (Chalmers et al. 2002)
Definitions A meta-analysis is defined as: “The statistical synthesis of the data from separate but comparable studies leading to a quantitative summary of the pooled results.” (Chalmers et al. 2002.)
Definitions A Systematic Review Production Model is defined as: The systematic and replicable organization of human and financial resources to achieve efficiency, cost effectiveness, and economies of scale in producing systematic reviews. (Turner et al., 2006)
Methods • Developed Target List of Organizations • Inclusion Criteria: SR as core or important • Personnel Communication - Phone calls - Emails • Literature Search
Results • Identified 18 organizations • Divided data collection into two Rounds • Report results from Round One
Organizations Identified Note. Numbers in parenthesis count organizations that will be included in round two of data collection.
1980 2000 C2 1994 CRD 1995 JBI 2006 1987 SCTA Development of the Field of Systematic Reviewing Inside US Outside US: (Sweden, CA, UK, AU)1 1999 CERM 1988 CSLP 1993 C1 EPPI 2002 WWC BVP(US) 1Not shown are organizations that will be included in round 2 of data collection: CDC GAO, Policy Hub, UK Home Office, DE&S, SSIE, and NICE.
Types of Organizations • Most organizations were government funded • Most organizations conduct contract reviews • Cochrane, Campbell, and Briggs conduct “interest” reviews
Typical Review Team(whether Interest or Contract) • Information Specialist • At Least Two Reviewers • Users* • Statistical Consultant* Accountability Support
The General Stages of a Review • Formulate review questions • Define inclusion and exclusion criteria * • Locate studies • Select studies • Assess study quality * • Extract data • Analyze and present results * • Interpret results *In Stages 2, 5, and 7 there is substantial variability across (and within) organizations.