1 / 1

Enhertu Price in India | 9310090915

Enhertu is used by healthcare professionals to treat patients with unresectable or metastatic HER2-positive breast cancer. Enhertu single-use vials come in 100 mg to administer intravenously. Fam-trastuzumab deruxtecan-nxki is a HER2-directed antibody and topoisomerase inhibitor conjugate. Fam-trastuzumab deruxtecan-nxki is an antibody-drug conjugate (ADC) composed of three components: <br>a humanized anti-HER2 IgG1 monoclonal antibody (mAb), covalently linked to <br>a topoisomerase inhibitor, via <br>a tetrapeptide-based cleavable linker. Deruxtecan is composed of a protease-cleavable maleimide tetrap

shalukimm
Download Presentation

Enhertu Price in India | 9310090915

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Enhertu: Dosage and Mechanism of action INDICATION AND USAGE For adults with HER2-positive breast cancer, which has spread to other parts of the body or cannot be removed by surgery, ENHERTU is used as prescribed by the doctor. It has proven itself an efficient drug for cancer that is sold at fairly good prices with uncompromised effects. It is available in the market, and anyone with a valid prescription can buy ENHERTU online in India. This effective drug is also given to adults suffering from HER2-positive advanced gastric cancer or gastroesophageal junction adenocarcinoma, which can be metastatic or has spread to other parts of the body. Enhertu is used in patients on its own who have taken one or more HER2-targeted treatments. DOSAGE AND ADMINISTRATION ENHERTU is a prescriptive drug that can only be obtained and used under the prescription and supervision of an expert cancer specialist doctor. The drug is available as ENHERTU 100 mg injection, which comes in lyophilized powder in a single-dose vial for reconstitution. ENHERTU is given intravenously only without any push or bolus. The recommended dose for HER2-positive breast cancer is 5.4 mg/kg once every 3 weeks of a 21-day cycle. For HER2-positive advanced gastric cancer, the recommended dosage of ENHERTU for gastric cancer is 6.4 mg/kg given by dripping the vein once every 3 weeks of a 21-day cycle. MECHANISM OF ACTION The active substance in Enhertu is trastuzumab deruxtecan. It is made up of two active components that are linked together. It is a HER2-directed antibody-drug conjugate. The antibody is a humanized anti-HER2 IgG1. DXd is a topoisomerase I inhibitor that is small in size and gets attached to the antibody by a cleavable linker. Its binding is followed by HER2 on tumor cells, by lysosomal enzymes, fam-trastuzumab deruxtecan undergoes internalization and intracellular linker cleavage. The membrane permeable DXd causes DNA damage and apoptotic cell death upon its release. The FDA approved fam-trastuzumab deruxtecan on August 5, 2022, for use in adult patients with unresectable or metastatic HER2-low breast cancer, and it is available in India. For more details about its mechanism of action and to check for ENHERTU price, you can visit us at Indian Pharma Network, +91 93100 90915. Source - https://helpforheallth.blogspot.com/2023/04/enhertu-targeted-medicine-for-her2- low.html

More Related