1 / 13

IAPCOI Subcommittee on Evidence based Recommendations (EBR) 2011-2013

IAPCOI Subcommittee on Evidence based Recommendations (EBR) 2011-2013. IAPCOI Subcommittee on Evidence based Recommendations (EBR): Formed on 24-25 Dec 2011. Chair: T. Jacob John Convener: Panna Choudhury Co-Convener : Nitin Shah Members: Vipin M. Vashishtha, Suhas Prabhu, S. G. Kasi

shania
Download Presentation

IAPCOI Subcommittee on Evidence based Recommendations (EBR) 2011-2013

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. IAPCOI Subcommittee on Evidence based Recommendations (EBR)2011-2013

  2. IAPCOI Subcommittee on Evidence based Recommendations (EBR): Formed on 24-25 Dec 2011 • Chair: T. Jacob John • Convener: Panna Choudhury • Co-Convener: Nitin Shah • Members: Vipin M. Vashishtha, Suhas Prabhu, S. G. Kasi •  Expert advisors: HPS Sachdev; Piyush Gupta; Dheeraj Shah

  3. Aims and Objectives • To develop a uniform approach to making explicit the evidence base for IAPCOI recommendations • To develop, evaluate and apply a system to make evidence based recommendations (both existing and future) for IAP COI.

  4. IAPCOI subcommittee of EBR Meeting Venue: IMA, New Delhi Date: 19-02-2012 • Dr. T. Jacob John), Dr. Vipin M Vashishtha;Dr. Panna Choudhury;Dr. H.P.S. Sachdev;Dr. Piyush Gupta ;Dr. S.G. Kasi;Dr. Dheeraj;Dr. A.J. Chitkara (Special Invitee); Dr. Shyam Kukreja (Special Invitee); Dr. Nitin Shah (Co-Convener EBR) and Dr. Suhas Prabhu (Member EBR) expressed inability to attend the meet.

  5. Salient points of minutes (1): Code of Conduct and Conflict of Interest • EBR committee will follow code of conduct as decided by IAPCOI……………….. all office bearers and members of IAPCOI (including its subcommittees) should disclose any financial, professional or other interests…….. • CIAP will appoint a committee of 3-5 eminent and neutral persons to decide whether the competing interests are significant enough to preclude the expert from participation in the deliberations of IAPCOI

  6. Salient points of minutes (2): Guidelines for EBR to be followed Guidelines for Evidence based review are available from ACIP, SAGE/WHO, ECDC. It was agreed to broadly follow the adapted model of WHO Guidelines. GRADE approach would be followed for scoring the quality of evidence. It is noted that working group at WHO requires 6-12 months for addressing 1 recommendation, ultimate work are mostly outsourced.

  7. Salient points of minutes (3): The key activities involved in creating evidence-based recommendations by IAPCOI should be as follows i) Definition of the questions to inform recommendations. ii) Identification of the critical questions for which an in-depth review of evidence is needed. iii) Systematic review of the literature with or without meta-analysis. iv) Review the quality of the evidence, in particular through assessment of the risk of bias and confounding. v) Scoring of the quality of the evidence (using the GRADE approach) for data on safety and effectiveness. vi) Discussion, deliberation and formulation of recommendation by IAP COI. vii) Submission of recommendation of IAP COI to IAP EB.

  8. Salient points of minutes (4): Process…. • As per WHO Guidelines GRADE scoring can be done for no more than 5 critical questions. • IAPCOI also need to identify mechanism how these critical questions would be addressed through GRADE approach either by outsourcing or identifying person/personssupported with reasonable remuneration or volunteers with credibility in this field(It is pointed out that it is hugely costly when outsourced ). 

  9. IAPCOI identified two specific issues: Burden of Rotavirus diarrhea in India and efficacy of current rotavirus vaccines in India On 24th May, 2012 IAPCOI/CIAP identified persons for doing the systematic review of burden of rotavirus diarrhea in under five children.

  10. Research Questions being addressed • Identification of the proportion of diarrheal diseases caused by rotavirus in hospitals • Identification of the proportion of diarrheal diseases caused by rotavirus in community • Case fatality of rotavirus disease measured among hospitalized children and community • Identification of molecular epidemiology of rotavirus diarrhea in under-five children of India’

  11. Data Sources under Search • The primary databases searched were Medline through PubMedand IndMed • Other sources including National Sample Survey, WHO, UNICEF, National Family Health Survey and Ministry of Health and Family Welfare • Related articles and the reference lists of included publications to identify additional studies • Not included: any unpublished data, data available within specific institutions at the national, state or local level, or data unavailable in the public domain

  12. TABLE I RESEARCH QUESTIONS AND SEARCH STRINGS USED

  13. Full text articles have been analyzed in the following format (Table 2) TABLE 2 SUMMARY OF ARTICLES

More Related