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Georgetown University. Chuck Wolfe wolfec@georgetown.edu. Campus Description. Medical Center (GUMC) 8 Research Buildings Main Campus 32 Campus Buildings including Dorms,Staff and Academic 6 Ancillary Buildings connected via 100Mbps. GUMC Network. Gigabit Core
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Georgetown University Chuck Wolfe wolfec@georgetown.edu
Campus Description • Medical Center (GUMC) • 8 Research Buildings • Main Campus • 32 Campus Buildings including Dorms,Staff and Academic • 6 Ancillary Buildings connected via 100Mbps
GUMC Network • Gigabit Core • Building Distribution Frames (BDFs) have a Dual Gigabit connection to the core • Floor Switches have a Gigabit connection to the BDFs • User provided with 10/100 connection
Main Campus Network • OC-12 ATM core • Server Farm has OC-12 connections to the core • BDFs have dual OC-3 connections to the core • Floor Switches have 100-200Mbps links to the BDFs • User provided with 10 or 10/100 connection
Remote Site Connections • OC-3 ATM • Frame-Relay • FNS (10Mbps) • T-1
Internet 2 • Connected via ATM utilizing Unspecified Bit Rate (UBR) • Primary connection to Abilene through MAX • Currently being used to test teleradiology application in the study of ALD
What is ALD? • Adrenoleukodystrophy is a rare genetic disorder that is often fatal in young boys. • It affects 1 in 20,000 people world-wide • A neurological disorder that destroys the myelin in the brain • Myelin insulates nerves and allows conduction of impulses between parts of the body • MRI permits early detection of nervous system damage and is a sensitive indicator of disease progression
Why are Multi-Center Clinical Trials Needed • No institution has enough patients to perform a randomized control study • ALD trained physicians are few due to the rarity of disease • Sharing of film images is difficult in an analogue world
Solution – Digital ALD MRI Network • Multiple sites can send data to a centralized database • Consolidation of data provides sufficient patient pool for therapy evaluation • ALD trained physicians have immediate remote access to the exams
Project Description • Development of DICOM network • DICOM database resides at KKI • Receives MRI studies from multiple institutions in US and world-wide • Permits query/retrieve of studies by ALD trained physicians for review • Utilizes secure technologies to ensure patient confidentiality and data integrity • Works over standard Internet and NGI
UMN –ISIS – KKI • Requested data from UMN over NGI • Upon receipt, immediately sent it to KKI over standard Internet • Recorded transmission times • Ran the test 7 times • Results: • ISIS – UMN averaged 242.5 seconds • ISIS – KKI averaged 2062.2 seconds
Transmission Time UMN – ISIS – KKI(Seconds) ISIS – KKI 45 miles UMN – ISIS 1100 miles
ISIS – KKI • Requested studies from KKI DICOM server to ISIS • Ran the test 78 times over standard Internet • Ran the test 83 times over NGI
NGI =296 n=83 Internet =67 N=78 Throughput: Internet vs. NGI
Results • Moving digital images is better than using film for sharing information • Standard Internet is unpredictable for moving large data sets • NGI supports real-time teleradiology • Future enhancements of the NGI will be evaluated
Current Projects at GU • Wireless Testing with authentication to LDAP • VoIP • Multicasting • QOS • Gigabit Connection to the Internet
Thanks to Betty Levine and MaryLou Ingeholm in ISIS for ALD testing info