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Hepatitis A and Hepatitis B Vaccination in High Risk Adults: Florida’s Experience with Integrating Services Accountability, Series Completion, and Early Program Evaluation. Sandra W. Roush, MT, MPH National Immunization Conference Nashville 5/2004. Holmes. Jackson. Escambia. H. o. l.
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Hepatitis A and Hepatitis B Vaccination in High Risk Adults: Florida’s Experience with Integrating ServicesAccountability, Series Completion, and Early Program Evaluation Sandra W. Roush, MT, MPH National Immunization Conference Nashville 5/2004
Holmes Jackson Escambia H o l m e s Santa Rosa J a c k s o n S a n t a R o s a Nassau W a l t o n Okaloosa Walton Washington Gadsden N a s s a u W a s h i n g o G a d s d e n Leon Hamilton Jefferson H a m i l t o n Madison Calhoun L e o n M a d i s o n J e f f e r s o n Duval B a k e r Baker D u v a l Liberty Suwannee Columbia Wakulla S u w a n n e e Taylor C o l u m b i a W a k u l l a Clay T a y l o r Bay Union Lafayette St. John’s U n i o n C l a y Gulf Bradford L a f a y e t t e Franklin S t J o h n s Florida: The Sunshine State B r a d f o r d F r a n k l i n Gilchrist i l c h r i s t Alachua A l a c h u a Putnam P u t n a m Dixie Flagler F l a g l e r Levy Marion M a r i o n Volusia V o l u s i a Citrus C i t r u s L a k e Sumter Lake Seminole S e m i n o l e u m t e r Hernando Orange O r a n g e B r e v a r d Pasco • 17+ million population • 67 counties ( 9 funded ) • Hepatitis A rates 5.89 (2001), 5.32 (2002), and 1.94 (2003) per 100,000 • Hepatitis B rates 3.45 (2001), 3.25 (2002), and 3.15 (2003) • Estimates indicate over 300,000 Floridians infected with hepatitis C Osceola Hillsborough i l l s b o r o u g h Polk Brevard O s c e o l a Pinellas P o l k Indian River I n d i a n R i v e r Manatee Okeechobee Hardee H a r d e e O k e e c h o b e e St. Lucie M a n a t e e S t L u c i e Highlands Desoto H i g h l a n d s D e S o t o Sarasota Martin r o t a Charlotte Glades C h a r l o t e t G l a d e s Hendry Palm Beach Lee P a l m B e a c h Broward Collier B r o w a r d Monroe Miami- Dade D a d e
Florida’s Hepatitis (A, B, C) Program • Providing leadership, policy development, and technical assistance • Development of a comprehensive prevention plan • Counseling and testing services • Vaccination for adults • Patient care services • Prevention initiatives • Allocating state hepatitis resources
Florida’s Statewide High Risk Adult Hepatitis Immunization Program • Initial purchase Dec. 2000 with carry over funds • 30,120 doses B ($ 700,290) • 946 doses A ($ 15,306) • Subsequent purchases: state and federal • Eligibility: adult high risk (STD, HIV, family planning, jail, outreach, epidemiology, immunization, hepatitis, etc.) • Statewide memos March 2001 and Dec. 2002 • NO CHARGE TO CHD OR CLIENT • Current monthly average for vaccine shipment : 1,175 hepatitis A; 2,163 hepatitis B
Florida Adult Hepatitis Vaccine Management 2000 – 2003 $ 1,828,151 $ 812,289 79,492 46,470 Number of Doses 70,211 40,332 68,974 34,167 • * Combined vaccine was also purchased: 2,330 doses ($ 82,374)
CY 2003 Adult Program Hepatitis A Vaccine Accountability* • 96 % hepatitis A vaccine accountability • 18,288 total doses required accountability • 5,526 doses in CHD refrigerators 1/1/03 • 12,901 doses distributed • 139 doses wasted • 17,746 total doses in accounting • 13,835 coded/used • 3,911 in CHD refrigerators 12/31/03 * 820 doses (4%) unaccounted
CY 2003 Adult Program Hepatitis B Vaccine Accountability* • 96 % hepatitis B vaccine accountability • 35,033 total doses required accountability • 5,573 doses in CHD refrigerators 1/1/03 • 29,823 doses distributed • 363 doses wasted • 34,536 total doses in accounting • 29,567 coded/used • 4,969 in CHD refrigerators 12/31/03 * 1,499 doses (4%) unaccounted
Adult Hepatitis A Vaccine Used/Coded November 1, 2000 to December 31, 2003
Hepatitis A Vaccine Doses and Series Completion in High Risk Adults: 67 Counties 25% 15% Number of Doses 20%
Hepatitis A Number of Doses and Series Completion in High Risk Adults: Selected Counties CY 2001 CY 2002 CY 2003 Number of Doses
Adult Hepatitis B Vaccine Used/Coded November 1, 2000 to December 31, 2003 *Funded Counties 31% hepatitis B series completion during this time period **Unfunded Counties 25% hepatitis B series completion during this time period
Hepatitis B Vaccine Doses and Series Completion* in High Risk Adults: 67 counties 53% 57% 51% 52% Number of Doses 50% 48% *Series Completion: 2001 (24%); 2002 (27%); 2003 (30%)
Hepatitis B Vaccine Doses and Series Completion in High Risk Adults:Selected Counties CY 2002 CY 2001 CY 2003 Number of Doses
Adult Hepatitis Vaccine and Testing Program: Early Program Evaluation • Chart review process similar to quality improvement • Clients seen Nov 1, 2001- Oct 31, 2002 • Demographics, doses received/dates, test results, results received, risk factors, medical/social referral • As of 11/6/2003, 1,541 charts reviewed in 11 counties • 9 site types (family planning, general, hepatitis, HIV, immunization, outreach, primary care, TB, STD) • Randomly selected charts within clinic type • Number of charts selected is based on county population contribution
Clients’ Use of Hepatitis A Vaccine November 1, 2001 – October 31, 2002 • Dose 1 • 54 % of lab eligible (228/419) • 26 % of risk assessment eligible (341/1309) • 72 % of HCV positive (52/72) • Dose 2 • 30 % of lab eligible (125/419) • 13 % of risk assessment eligible (175/1309) • 49 % of HCV positive (35/72)
Clients’ Use of Hepatitis B VaccineNovember 1, 2001 – October 31, 2002 • Dose 1 • 58 % of lab eligible (288/501) • 35 % of risk assessment eligible (451/1309) • 72 % of HCV positive (52/72) • Dose 2 • 42 % of lab eligible (210/501) • 24 % of risk assessment eligible (309/1309) • 57 % of HCV positive (41/72) • Dose 3 • 25 % of lab eligible (126/501) • 14 % of risk assessment eligible (184/1309) • 39% of HCV positive (28/72)
Date Appropriate Hepatitis Vaccination* November 1, 2001 – October 31, 2002 • Hepatitis A • 25 % of lab eligible (103/419) • 12 % of risk assessment eligible (160/1309) • 35 % of HCV positive (25/72) • Hepatitis B • 25 % of lab eligible (123/501) • 16 % of risk assessment eligible (205/1309) • 31 % of HCV positive (22/72) * Among those starting vaccine
Date-Appropriate Adult Hepatitis A Vaccination by Clinic Site
Date-Appropriate Adult Hepatitis B Vaccination by Clinic Site
Hepatitis Testing for Florida Adults at Risk • Statewide ABC panel (“chronic panel”) • Hepatitis A (anti-HAV total) added 2/9/04 • Hepatitis B (HBsAg, HBsAb, HBcAb) • HCV • Anti-HCV with signal-to-cut-off ratio • Polymerase chain reaction (PCR) and/or recombinant immunoassay (RIBA™) • Pricing considerations • Medicaid • Signal-to-cut-off ratio
Florida Chronic Hepatitis Testing Program: Results Summary* • Number (percent) based on n=26,241 “chronic panels” Jan. 2001 – Dec. 2003
Next Steps: Florida’s Adult Hepatitis A and B Immunization Program • Vaccine accountability mechanisms • Coverage assessment • Evaluation • Feasibility • Cost effectiveness/efficiency • Expand to additional clinics and other sites • Ensure a reliable vaccine supply