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Randy H. Weiss, Ph.D. Partner, Triathlon Medical Ventures. Life Science Venture Capital 11th Annual NIH SBIR/STTR Conference July 1, 2009. Background. Partner, Triathlon Medical Ventures Fund I is $105M (17 investments; raising Fund II) Focus on early-stage biomedical investments in Midwest
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Randy H. Weiss, Ph.D. Partner, Triathlon Medical Ventures Life Science Venture Capital11th Annual NIH SBIR/STTR ConferenceJuly 1, 2009
Background • Partner, Triathlon Medical Ventures • Fund I is $105M (17 investments; raising Fund II) • Focus on early-stage biomedical investments in Midwest • Member, St. Louis Arch Angels • Co-founder and Board Chair for Cardialen • Implantable medical device for painless treatment of atrial fibrillation and flutter (spin-out of Washington Univ. in St. Louis) • Co-founder, Interim CEO, Board Chair of Vasculox • Biopharmaceuticals for organ transplantation (spin-out of Washington Univ. in St. Louis) • Entrepreneur-in-Residence, U. of Iowa Research Foundation 11th Annual NIH SBIR/STTR Conference
What are VCs Looking For? • Innovative technology that enables a competitive market advantage over current and emerging products • Products that address significant and recognized unmet needs in large and growing markets • Strong and defensible intellectual property with freedom to operate or other barriers to market entry • Development plan that can be achieved with accessible capital to provide an exit with attractive returns in a reasonable timeframe • Successful, experienced management team 11th Annual NIH SBIR/STTR Conference
Potential for High Growth Companies • High Potential: • Innovative, disruptive technology • Exit greater than $100 million (medical devices) or $200 million (pharma/biotechnology) • Large up-side potential but with high risk • Capital needs might be $25M or more • Expected multiples of >2.5x • Exit in 3-7 year timeframe • Strong VC interest • Less angel investor interest • Example: Pharmaceutical company has plans to advance pre-clinical drug candidate through Phase II clinicals 11th Annual NIH SBIR/STTR Conference
Potential for High Growth Companies • Medium Potential: • Incremental improvement in technology • Exit between $10 million and $100 million (healthcare services, medical products/IT) • Up-side potential may be capped but with lower perceived risk, earlier revenue expectation, and lower capital needs • Exit within 3-5 years • Strong angel investor interest with some VC interest • Expected multiples of >10x • Example: Medical software firm has plan to ramp-up revenues to $3M in 2-3 years 11th Annual NIH SBIR/STTR Conference
What Do VCs Expect in Return? • Invest in a company, not a research project , with a well-defined business plan and management team that can execute the plan • Ownership in the company • Opportunity to invest in follow-on rounds • Seat on the board (assuming a substantial investment) with voting rights to allow for control over the company • Defined exit strategy that provide attractive returns on investment in an acceptable amount of time and with acceptable risk 11th Annual NIH SBIR/STTR Conference
Investment Process • Submit Executive Summary or Business Plan • One or more individuals of investor group will screen opportunity • Invitation to present to entire investor group • Due diligence (under confidentiality) • Term sheet submitted by lead investor(s) • Negotiation of term sheet • Additional follow-on investors identified • Closing of investment 11th Annual NIH SBIR/STTR Conference
Corporate/Legal Management Science & Technology Intellectual Property Manufacturing/Product Development Clinical/Regulatory Market/Sales Business Development Finance/Investment Shareholders/Board of Directors Due Diligence 11th Annual NIH SBIR/STTR Conference