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Psikopatoloji

Psikopatoloji. Prof Dr Süheyla ÜNAL. Psychopathology -1. Content. psychodynamic, behavioral and cognitive theories of abnormal behavior biological explanations of psychiatric disease. Aim.

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Psikopatoloji

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  1. Psikopatoloji Prof Dr Süheyla ÜNAL Psychopathology-1

  2. Content psychodynamic, behavioral and cognitive theories of abnormal behavior biological explanations of psychiatric disease

  3. Aim At the end of the training period the student will comprehend biopsychosocial factors which cause psychopathology and will get information about different psychopathological theories

  4. Objectives Student will; • define psychodynamic, behavioral and cognitive theories of abnormal behavior • discuss explanatory features of basic psychopathological theories, • evaluate risk factors, pathogenesis and diagnostic criterion of psychiatric disease • make biopsychosocial evaluation

  5. Mental disease criteria • Bizarreness of Behavior • Persistence of Behavior • Social Deviance • Subjective Distress • Being Dangerous • Effect on Functioning Normal Abnormal

  6. 3D criteria • 3 criteria for abnormality be referring to them as “the three D’s” • Deviance • Dysfunction • Distress

  7. Seligman et al., criteria • Suffering • Maladaptiveness • Irrationality and incomprehensibility • Unpredictability and loss of control • Vividness and unconventionality • Observer discomfort • Violation of moral and ideal standards

  8. Psychopathology Defines a problematic condition in mood, thought and behavior • There is a function defeat in home, work and social life • It causes distress in person’s himself or around the person

  9. Mental Theories Psychodynamic Unconscious conflicts between primitive desires and limits originating from mental disease Mental disease’s symptoms occur when some original behaviors are strengthen and punished Behavioral People’s themselves and their negative beliefs about the world and other people cause negative sensation and behaviors Cognitive

  10. Biological explanations • Altering in the brain chemistry, can alter thecognition,mood and behaviour Brain chemistry Behaviour Mood Cognition

  11. Diatez-stress model • Gene-environment interaction Existence of stress + Genetic vulnerability Illness Absence of stress Health -

  12. Neurotransmission Mechanisms

  13. Neurotransmission

  14. Mechanisms effecting synaptic transmission Changes in molecular structure Excess neurotransmission Low neurotransmission Imbalances of neurotransmitters Error in neuronal network Loss of neuronal plastisite

  15. Alterations in molecular structure

  16. Neurotransmitter-Symptom ‘Psychomotor agitation’ ‘Agression’ 5-HT, GABA 5-HT, GABA ‘Apathy’ ACh 5-HT,DA 5-HT ‘Psychosis’ ‘Depression’

  17. Cognitive functions-Illness Perception Psychosis Sensation Social function Cognition Dementia Depression Parkinson Motor function

  18. Excess neurotransmission

  19. Excess neurotransmission

  20. Vernacular blood stream in bipolar defeat • Depression • Mania • Depression (Baxter et al 1985) 22

  21. Results of excess neurotransmission

  22. Results of excess neurotransmission

  23. Excess pruning

  24. Normal schizophrenia Excess pruning

  25. Low neurotransmission

  26. Low neurotransmission

  27. Neurotrophic factors

  28. Depression

  29. Stress effects to hyppocampus

  30. Stressful life events in childhood Present living conditions Depression Thought Belief systems Basic assumptions STRESS Genetics Physical functions

  31. Oxidative stress

  32. Wrong Networks

  33. QUESTION Which of this is a pathology related with low neurotransmission? • Panic attack • Hypomani • Excitation • Lack of attention • Delusion

  34. QUESTION Increase in noradrenergic neurotransmission from locus ceruleus to limbic system cause to …. a- Illusion b- Hallucination c- Panic d- Obsession e- Depression

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