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Welcome!

Welcome!. Esophageal Health, Acid Reflux, Barrett’s and Cancer Philip N Styne, MD AGAF Medical Director Digestive Health Center. Upper GI tract. Function of upper GI anatomy. Esophagus - passes food and fluid from mouth to stomach Stomach - mechanical and enzymatic digestion.

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Welcome!

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  1. Welcome! • Esophageal Health, • Acid Reflux, Barrett’s and Cancer • Philip N Styne, MD AGAF • Medical Director • Digestive Health Center

  2. Upper GI tract

  3. Function of upper GI anatomy • Esophagus - passes food and fluid from mouth to stomach • Stomach - mechanical and enzymatic digestion

  4. Function of upper GI anatomy • Pancreas & liver - digestive enzymes and detergents • Small intestine - absorbs salts, vitamins, minerals and food

  5. Gastroesophageal Reflux • Abnormal return of food, fluid, acid and digestive enzymes into the esophagus.

  6. Gastroesophageal Reflux • Acid has both digestive and protective role • Lining of the esophagus does not make acid, has no barrier to acid exposure • Lining of stomach makes acid and has its own acid barrier

  7. Gastroesophageal Reflux • Esophagogastric junction three-part system to control reflux of gastric contents into the esophagus

  8. Gastroesophageal Reflux • Reflux results in: • Heartburn • Inflammation • Stricture • Barrett’s Esophagus • Asthma, cough, throat clearing and hoarseness

  9. Lifestyle Changes • Nutrition • What, when & how much? • Diets consisting mainly of green and yellow vegetables • Small meals • Nothing to eat for 3 hours before bedtime

  10. Lifestyle Changes • Diet • Maintaining a healthy weight • Low fat meals • Limited alcohol • No tobacco products

  11. Lifestyle Changes • Walking after evening meal for 20 minutes • Elevation of the head of the bed

  12. Medication • Acid reduction reduces symptoms and esophageal inflammation • Antacids • H2RA • PPI • Prokinetics

  13. Barrett’s Esophagus • Result of reflux • Precursor of Esophageal Cancer • Predictable changes before Cancer • Treatable with endoscopic procedure

  14. Barrett’s Esophagus • Due to chronic reflux: • Risk of cancer • Adenocarcinoma which is associated with Barrett’s is the fastest increasing gastrointestinal cancer.

  15. Esophageal Cancer • Fastest rising rate of all gastrointestinal cancers. • The cancer associated with Barrett’s Esophagus has increased over 400%.

  16. Our Goal: • Prevent cancer morbidity and mortality. • Reduce occurrence and find earlier more curable stage.

  17. Endoscopy • Allows evaluation of the lining of the upper-intestinal tract • Allows for biopsy of the esophagus

  18. Endoscopy

  19. Endoscopy

  20. Endoscopy Acid Reflux Normal Esophagus Barrett’s Esophagus Esophageal Cancer

  21. Ulcers & Itis • Barrier breakers result in inflammation of stomach and duodenum including ulcers • ASA\NSAID\Cox 2 inhibitor have the ability to affect gastric acid barrier • Helicobacter pylori

  22. Ulcers & Itis • Small intestine disease • Celiac sprue, gluten sensitivity • Lactose intolerance • Other carbohydrate malabsorption • Giardia • Bacterial overgrowth

  23. Questions? For more information visit: www.FHDigestive.com Information sheets and priority appointments available.

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