110 likes | 125 Views
Explore modifying knee models to analyze knee malalignment in obese individuals and its impact on biomechanics. Discuss optimization methods and joint contact force distribution for research.
E N D
Simulation of Obese Locomotion Biomechanics • Workshop Goals: • Investigate the effects of individual muscle strength scaling on muscle force production and joint reaction forces • Refine our weighted static optimization API code to read in settings from an XML file • Knee able to resolve med-lat joint contact force distribution • Must incorporate knee alignment >> Modify Knee Model • Discuss predictive optimization approaches (over beer)
Modeling Static Knee Alignment: Motivation • Obese children have ~3X greater prevalence of knee malalignment vs. NO • Malalignement as Obese adult >> much greater risk for development and progression of OA • We want to quantify both the magnitude and the distribution of the knee joint contact force
Modeling Static Knee Alignment What is the correct anatomical alignment? ?
Modeling Static Knee Alignment θ • For this exercise, we kept the tibiofemoral joint parallel to the ground • Added two bodies (femoral condyles, tibial plateau) • Updated joint definitions (articulations) Varus alignment
Modeling Static Knee Alignment • Also made a model with valgus alignment
Modeling Static Knee Alignment Check: Make sure muscles aren’t passively stretched i.e. musculo-tendon unit is the same between a neutral and malaligned knee e.g. Semitendinosus
Modeling Static Knee Alignment • Reran IK>RRA>SO>JR for Valgus, Varus, and Neutral Alignment
Modeling Static Knee Alignment • Axial Force • Largest with Varus alignment (Not Expected, I expected neutral) Result of forcing alignment on neutral subject
Modeling Static Knee Alignment • Knee Abd/Add Moment • Largest with Varus alignment (Expected, Obvious) Abd Add
Modeling Static Knee Alignment • Proof of Concept: Can incorporate radiographic knee alignment to better understand loading in future childhood obesity study • Take home message: Critical to incorporate frontal plane knee alignment if you intend to calculate medial-lateral distribution! • Future: • Balance forces and moments to resolve *approximate* medial-lateral distribution • Incorporate med-lat calculation in a JR plugin