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Schlenk

Question 1-2: Please comment on whether appropriate background information is provided and accurately characterized. Please provide any other significant literature, reports, or data that would be useful to complete this characterization, and if so, what are they?. Schlenk. Overview.

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Schlenk

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  1. Question 1-2: Please comment on whether appropriate background information is provided and accurately characterized. Please provide any other significant literature, reports, or data that would be useful to complete this characterization, and if so, what are they? Schlenk

  2. Overview • Background and rationale for assessment logical • Issues • Developmental Tox? (mammalian vs. non-mammalian) • AOP analyses? (EDC/Developmental/Reproduction) • QA/QC (MDL and ND) • Unit inconsistencies (wet wt. vs. dry wt.) • Production vs. Predicted Environmental Concentrations • Definitions • Sorption vs. adsorption

  3. Overview • Conceptual Model • No Problem Formulation Section (Screening?) • Fate • Wastewater dominated Stream (FW worst case) • Influence of Treatment on Detection levels • Leachate from Biosolids • Dietary uptake (plant or animal uptake from seds/soil) • Field derived BAFs • Marine and FW organisms should be separate • Transformation • Anaerobic Degradation • Metabolite Characterization • Air • Rationale for Human Health (WOE/EDC) • Bird/Mammal as receptors of interest?

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