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signal?. anti- . Z. sigZ. rsiZ. P Z. P ?. M. P Z. cszA. cszB. P ?. P Z. cszC. Figure 1. E. E Regulon. OM. B. B. A. A. IM. E. Folding catalysts. rpoE. rseA rseB rseC. P E. Figure 2. fecI. Fe-citrate. OM. A. R. R. BCDE. IM. FecI. Fe.
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signal? anti- Z sigZ rsiZ PZ P? M PZ cszA cszB P? PZ cszC Figure 1
E E Regulon OM B B A A IM E Folding catalysts rpoE rseA rseB rseC PE Figure 2
fecI Fe-citrate OM A R R BCDE IM FecI Fe Fur P PFecI fecI fecR fecABCDE Figure 3
-P O CH2 CH2OCCH-NH3+ CH2 CH3 O -P CAMPs (+) dlt operon WTA O LTA PG - - - - - - - -+ - + - -- - - - - - - + -- - +-- ++ -- -- - +-- + M DAG-P OCH2CH2-NH3+ - - - - - - - - + - - - +- - - - - +- - - -- + --- - -- -- -+- +-- + pss-psd operon Figure 4
AbrB Cell wall stress: e.g. vancomycin anti- W PW sigW rsiW PW pbpE PW W regulon Spo0A-P fosB PW M Phosphorelay (Sporulation) sppA etc. Figure 5
me cell wall Cell wall stress: e.g. vancomycin C membrane CseB--P CseB • cell wall glycan • (cwg) operon • other functions P sigE cseA cseB cseC sE Figure 6
RsrA S-S Zn(II) Thioredoxin System disulfide stress: e.g. diamide sR sR Zn(II) PR sigR rsrA Figure 7