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SBML-PET-MPI: A parallel parameter estimation tool for SBML models

SBML-PET-MPI: A parallel parameter estimation tool for SBML models. Features of SBML-PET-MPI Fast: speed up with multiple processors (MPI protocol). Less than 5 min for the Epo model with 7 cpus. Estimates parameter values by fitting multiple experimental data sets.

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SBML-PET-MPI: A parallel parameter estimation tool for SBML models

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  1. SBML-PET-MPI: A parallel parameter estimation tool for SBML models Features of SBML-PET-MPI • Fast: speed up with multiple processors (MPI protocol). Less than 5 min for the Epo model with 7 cpus. • Estimates parameter values by fitting multiple experimental data sets. • Peform uncertainty and identifiability analysis of the estimated parameters with profile likelihood exploit algorithm or bootstrap method with synthetic data sets. Reference: Zi Z., SBML-PET-MPI: A parallel parameter estimation tool for Systems Biology Markup Language (SBML) based models, Bioinformatics, 2011 (In press) Speed up of SBML-PET-MPI Test model: Epo model, Becker et al., Science, 2010 Data fitting result from SBML-PET-MPI

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