PREPACKED CHROMATOGRAPHY COLUMNS MARKET ANALYSIS

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2. Prepacked Chromatography Columns Market, By Product Type (1–100 mL, 100–1000 mL, >1L), By Technique (Hydrophobic Stationary Phase, Ion Exchange Chromatography, Affinity Chromatography, Multimodal Chromatography, Gel Filtration, Others), By Application (Sample Preparation, Resin Screening, Protein Purification, Anion and Cation Exchange, Desalting), By End User (Pharmaceutical Biotechnology, Food and Beverage, Agriculture and Environmental, Nutraceutical, Academics  and Research, Analytical laboratories), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East & Africa) - Size, Share, Outlook, and Opportunity Analysis, 2020 - 2027 PREPACKED CHROMATOGRAPHY COLUMNS MARKET ANALYSIS

3. Prepacked chromatography columns find application in the biopharmaceuticals sector and are used in separating molecules, purifying proteins, and other applications. These columns are available in various sizes depending on the type of application such as high throughput screening, process development, bench-scale screening, and preparative chromatography. Statistics: The global prepacked chromatography columns market is estimated to account for US$ 4,263.5 Mn in terms of value by the end of 2027. Global Prepacked Chromatography Columns Market: Drivers Increasing R&D and launch of biopharmaceutical drugs is expected to propel growth of the global prepacked chromatography columns market over the forecast period. For instance, according to Pharmaceutical Research and Manufacturers of America, over 750 orphan drugs were approved in the U.S. in 2018, compared to over 600 in 2017. Moreover, increasing need for purification of biopharmaceuticals is also expected to aid in growth of the market. Biopharmaceuticals require exceptional purity, thereby making downstream process a critical component of the overall process. Screening and purification play an important role in the manufacture of biopharmaceutical drugs. Statistics: North America held dominant position in the global prepacked chromatography columns market in 2019, accounting for 33.3% share in terms of value, followed by Asia Pacific and Europe, respectively

4. Global Prepacked Chromatography Columns Market Share (%), by Value, by Region, 2019

5. Global Prepacked Chromatography Columns Market: Restraints Fouling and clogging in prepacked chromatography columns is expected to limit growth of the market. Fouling and clogging reduce dynamic binding capacity and also increase the pressure drop across the columns. This decreases the life span of columns significantly. Back flush is possible in axial flow to reverse fouling and clogging. However, it is not possible with radial flow. Moreover, higher preference to conventional chromatography columns in emerging economies and high maintenance cost of reusable pre-packed chromatography columns is also expected to limit the market growth. Global Prepacked Chromatography Columns Market: Opportunities  Increasing R&D of biosimilars is expected to offer lucrative growth opportunities for players in the global prepacked chromatography columns market. For instance, in May 2018, Pfizer, Inc., a U.S.-based pharmaceutical company, received the U.S. Food and Drug Administration (FDA) approval for RETACRIT, which is a biosimilar to Epogen and Procrit. It is the first and only FDA approved biosimilar erythropoiesis-stimulating agent. Moreover, development of larger, lower-cost single-use pre-packed columns for large-scale clinical and commercial applications is also expected to aid in growth of the market. Statistics: The global prepacked chromatography columns market was valued at US$ 2,227.4 Mn in 2019 and is forecast to reach a value of US$ 4,263.5 Mn by 2027 at a CAGR of 8.5% between 2020 and 2027.

6. Global Prepacked Chromatography Columns Market Value (US$ Mn), and Y-o-Y Growth (%), 2019-2027

7. Market Trends/Key Takeaways >1L prepacked columns are being developed that provide technical, economic, and logistical advantages. Large prepacked columns are easy to set up, validate, and clean. These columns also reduce the amount of labor and time required in maintenance, increase productivity per run, and offer operational flexibility with rapid changeovers to the users. The adoption of multimodal chromatography columns is increasing due to enhanced selectivity that can be achieved during protein separations through this column as compared to traditional single-mode chromatography. It can be used for drugs that utilize proteins and are difficult to separate from other deadly impurities. The technique is also used in the downstream processing of monoclonal antibodies. Global Prepacked Chromatography Columns Market: Competitive Landscape Major players operating in the global prepacked chromatography columns market include, Agela Technologies (Danaher Corporation), Agilent Technologies Inc., Bio-Rad Laboratories, Inc., EMD Millipore (Merck KGaA), GE Healthcare, KNAUER WissenschaftlicheGeräte GmbH, Pall Corporation (Danaher Corporation), Phenomenex, Inc., Repligen Corporation, and Thermo Fisher Scientific, Inc. Global Prepacked Chromatography Columns Market: Key Developments Major players in the market are focused on adopting collaboration strategies to enhance their market share. For instance, in January 2020, Agilent Technologies Inc. collaborated with Indian Institute of Technology Delhi, India, to promote biopharmaceutical research. Major players in the market are also focused on adopting M&A strategies to expand their product portfolio. For instance, in April 2019, Repligen Corporation entered into a definitive agreement to acquire privately-held C Technologies, Inc. to expand its Process Analytics segment of bioprocessing.

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