1 / 17

Overview of Blood & Tissue Flagellates - Trypanosoma Species

Learn about Trypanosoma species causing sleeping sickness & Chagas disease. Understand their symptoms, diagnosis techniques & life cycles.

steveson
Download Presentation

Overview of Blood & Tissue Flagellates - Trypanosoma Species

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. BLOOD & TISSUE FLAGELLATES/HAEMOFLAGELLATESTrypanosomasp.Assistant lecturerAhmed Essam

  2. Trypanosoma sp. • T. bruceigambiense - cause: West African sleeping sickness • T. bruceirhodesiense - cause: East African sleeping sickness • T. cruzi - cause: American trypanosomiasis or ‘Chagas’ disease.

  3. T.b. gambiense frequently goes to CNS • Causes the chronic, sleepiness associated with African Sleeping Sickness • Apathy, mental dullness, disturbance of coordination • Increase in sleepiness, finally to coma, and death. • Death may also occur from malnutrition, falling, or other infections

  4. T.b. rhodiensienserarely invade the CNS but causes death much faster. • Usually due to invasion of heart tissue • Both subspecies produce intermittent periods of fever, particularly in early stages.

  5. T. brucei. gambiense • Cause West African sleeping sickness. • “tsetse fly belt” is a large area of Africa that has reported cases of African sleeping sickness. • Vector/ intermediate host:(Glossina) tsetsefly.

  6. T. bruceigambiense(Trypomastigotes)

  7. Tsetse fly (Glossina)

  8. West African sleeping sickness • Also known as Gambian trypanosomiasis. • Chronic course- ends with central nervous involvement and death after several years of durations.

  9. Life cycle of T.brucei

  10. Diagnosis 1. Microscopic examination:(Trypomastigotes in the blood smear). • Concentration technique – centrifugation • Serologic technique.

  11. T. burceirhodesiensi(trypomastigotes)

  12. T. cruzi • Cause of American trypanosomiasis/ (Chagas disease). • Has an intracellular amastigote stage that develops in cardiac, brain and visceral tissues. • Also has trypomastigotes in the peripheral circulation.

  13. T. cruzi

  14. Life cycle of T. cruzi

  15. Trypanosoma cruzi vector • Triatomine bug(kissing bug),, defecating on the wound after taking a blood meal

  16. Reduviid bug( - triatoma species

  17. Thank you

More Related