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Structure of the Circulatory System. Paul Buser , Courtney Green, Monica Roberts and Michelle Silver. Circulatory System a.k.a Cardiovascular. Main Function: Transport substances dissolved or suspended in the blood O 2 CO 2 Nutrients - digested food molecules
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Structure of the Circulatory System Paul Buser, Courtney Green, Monica Roberts and Michelle Silver
Circulatory System a.k.a Cardiovascular • Main Function: Transport substances dissolved or suspended in the blood • O2 • CO2 • Nutrients - digested food molecules • Cells of immune and other defense systems • Hormones
The Heartcentral pump for blood Right Atrium: receives de-oxygenated blood from veins (blood enters) Taken from body and sent to lungs to become rich in oxygen once more Left Atrium: Transfers oxygenated blood to the arteries (blood leaves) Taken from lungs, transferred to body Aorta Vena Cava Vena Cava
Types of Vessels in the body • Arteries/Arterioles - carry blood away from heart --> high pressure • Veins/Venules - carry blood back to the heart --> low pressure • Capillaries - provide the link between arterial and venous blood vessels, where diffusion occurs
Vein Artery Arteriole Venule Capillary
Arteries and Arterioles • Arteries (elastic and muscular) Muscular arteries are farther from heart, deliver blood to specific organ. Elastic arteries (aorta) hold more blood, take blood from the heart • Structure = large-diameter blood vessels, have smooth muscle • Function = efficiently transports oxygenated blood from the heart at high pressures, high pressure necessary to push blood, main force of blood to travel to tissues • Exception: pulmonary artery transports de-oxygenated blood to lungs • Arterioles • Structure = smaller-diameter than the arteries, connect to capillaries, have smooth muscle • Function = controls the volume of blood flow through organs
Three Levels of the Artery1. Tunica Intima: direct contact with blood, smooth/flat to minimize resistance of flow2. Tunica Media: muscle level, holds artery in place, deals with high pressure-->contracts to adjust pressure3. Tunica Adventitia: external layer, outer covering for protection
Veins and Venules • Veins- low resistant transport tubes to the heart • Structure = large in diameter, Valves + smooth muscles in the venous wall. Thinner than arteries because lower pressure • Function = valves prevent back flow of blood against gravity and smooth muscle controls venous pressure (low) and volume, thus allowing veins to serve as blood reservoirs. veins carry de-oxygenated blood to the heart • Exception: pulmonary vein carries oxygenated blood. • Low pressure of veins compliments high pressure of arteries • Venules (little veins) - Capillaries merge into venulesvenules then merge into the larger-diameter veins.
Vein: 3 Levels1. Tunica Intima- has valves, direct contact with blood, smooth/flat to minimize resistance2. Tunica Media- thinner smooth muscle than artery3. Tunica Adventitia- outer covering
Capillaries • Structure: very thin, fragile tubes • Only one cell thick, not visible without microscope • Function: exchange of CO2 and O2 through thin walls, connects arterioles and venules
Endothelial Cells • They are very flat with a central nucleus • Function • They play a major role in arterial diseases • Flat/slick to allow blood to flow with less resistance in all vessels • Act as a filter –they regulate the passage of gases, fluids, etc across their cell membranes. Most transports occur at capillary beds but a little bit occurs for muscles in arteries and veins Types of Cells that Line Blood Vessels • Different organs have different types of endothelial cells that allow more or less passage of necessary nutrients or gasses
Subcategories of Circulatory System • Systemic Circulation • Pulmonary Circulation • Portal Circulation
Systemic Circulationsupplies blood to all body tissues, exchange of nutrients and products of metabolism • Systemic arterial system- transfers oxygenated blood from heart to body tissues • Systemic venous system- returns de-oxygenated blood from tissues, rich in CO2, back to the heart *This is the system that blood pressure is measured in
Pulmonary Circulationmovement of blood between the heart and lungs • De-oxygenated blood brought back to the heart Vena Cavae --> Right Atrium --> Right Ventricle --> Pulmonary Artery --> Lungs • In lung capillaries there’s an exchange between CO2 and 02 • Fresh, oxygenated blood enters the heart Pulmonary Veins --> Left Atrium --> Left Ventricle --> Aorta --> body
Portal Circulation • The circulation of blood through larger vessels, from capillaries of one organ to capillaries of another organ *normally there is just one capillary bed for each branch of circuit, portal circulation has 2! EX: blood travels from the gastrointestinal tract and spleen to the liver: digested and absorbed substances from the gut go right to the liver to be synthesized/detoxify the blood
Blood Pressurethe force of the blood pushing against the walls of the arteries • Factors affecting blood pressure • - Gravity – pulls blood towards ground, heart pumping is needed to bring blood upwards. • Radius of the vessel – smooth muscle can change radius immediately if necessary. • Amount of blood: more viscous= higher pressure • Types of Blood pressure • Systolic is the peak blood pressure-when blood pumped • Diastolic is the lowest pressure when the blood is moving through the vessels-remaining pressure after blood is pumped, enough flow to keep things moving
Sources • Healthwise Incorporated. “Normal Heart.” Healthwise Incorporated. Aug. 2008. 10 Nov. 2009. <http://64.143.176.214/library/healthguide/en- us/support/topic.asp?hwid=aa54865> • McGeachie, Professor John. "Blue Histology - more about Endothelial Cells." School of Anatomy & Human Biology - Teaching Website Index. N.p., n.d. Web. 11 Nov. 2009. <http: //www.lab.anhb.uwa.edu.au/mb140/MoreAbout/ Endothel.htm>. • Ross, John. “Structure and Function of Blood Vessels.” Fortune City. July 1999. 10 Nov. 2009. <http://greenfield.fortunecity.com/rattler/46/vessels.htm> • Starr, Cecie and Ralph Taggart. Biology: The Unity and Diversity of Life 9th Edition. Pacific Grove, CA: Brooks/Cole, 2001. Print. • The Franklin Institute. “The Human Heart.” The Franklin Institute. 1996-2009. 10 Nov. 2009. <http://www.fi.edu/learn/heart/systems/pulmonary.html>