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Mutations

Mutations. Genetic Mutations.  Any mistake or change in the DNA base sequence is a and occur at random .  Any organism that is affected by a mutation is called a Any substance or agent that causes a mutation is a

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Mutations

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  1. Mutations

  2. Genetic Mutations •  Any mistake or change in the DNA base sequence • is a and occur at random. •  Any organism that is affected by a mutation • is called a • Any substance or agent that causes a • mutation is a • Ex: UV radiation, smoking, mutation mutant mutagen

  3. Types of Mutations

  4. Mutations Gene Point single • 1. mutation = a change in a base pair. • DNA (normal) AGG TGC CCT GGT TTA • DNA (mutated) AGG TCC CCT GGT TTA • Which amino acid was mutated? ______ • Threonine was changed to • Results in a change in a single _______ _______.

  5. Gene Mutations Point single • 1. mutation = a change in a base pair. • DNA (normal) AGG TGC CCT GGT TTA • DNA (mutated) AGG TCC CCT GGT TTA • Which amino acid was mutated? ______ • Threonine was changed to . • Results in a change in a single _______ _______. Second Arginine Amino acid

  6. Gene Mutations mutation: Occurs when a single base is or . DNA (normal) GGA TTG GAG TTA AGC DNA (mutated) GGA TTG GAG TAA GC Which type of mutation occurred? Which amino acid did it occur? __________ Frameshift deleted added

  7. Gene Mutations mutation: Occurs when a single base is or . DNA (normal) GGA TTG GAG TTA AGC DNA (mutated) GGA TTG GAG TAA GC Which type of mutation occurred? Which amino acid did it occur? ____________ Frameshift deleted added deletion 4th, T deleted

  8. Gene Mutations Frameshift mutation: Occurs when a single base is or . DNA (normal) AGT GTC TCG ATG GTA DNA (mutated) AGT GTC TCC GAT GGT A Which type of mutation occurred? Which amino acid did it occur? ___________ Results in a mutated from the point of addition or deletion. added deleted

  9. Gene Mutations Frameshift mutation: Occurs when a single base is or . DNA (normal) AGT GTC TCG ATG GTA DNA (mutated) AGT GTC TCC GAT GGT A Which type of mutation occurred? Which amino acid did it occur? ___________ Results in a mutated from the point of addition or deletion. added deleted addition 3rd, C added gene (protein)

  10. Mutations Chromosome meiosis mitosis Can occur during ________ or _________. Only mutations that occur during ,can be passed on to offspring. meiosis Deletion a. b. c. d. Duplication/ Addition Inversion Translocation

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